Evidence map›Paper›PMID 39534576›Full record

ArticleEvolutionary bioinformatics online2024

Israt Jahan Asha, Shipan Das Gupta, Md Murad Hossain, Md Nur Islam, Nurun Nahar Akter, Mohammed Mafizul Islam, Shuvo Chandra Das, Dhirendra Nath Barman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Evolutionary bioinformatics online, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Israt Jahan AshaDepartment of Biotechnology and Genetic Engineering, Noakhali Science and Technology University, Noakhali, Bangladesh.
Shipan Das GuptaDepartment of Biotechnology and Genetic Engineering, Noakhali Science and Technology University, Noakhali, Bangladesh.
Md Murad HossainDepartment of Biotechnology and Genetic Engineering, Noakhali Science and Technology University, Noakhali, Bangladesh.ORCID https://orcid.org/0009-0002-0852-9737
Md Nur IslamDepartment of Biotechnology and Genetic Engineering, Noakhali Science and Technology University, Noakhali, Bangladesh.
Nurun Nahar AkterDepartment of Biotechnology and Genetic Engineering, Noakhali Science and Technology University, Noakhali, Bangladesh.
Mohammed Mafizul IslamDepartment of Biotechnology and Genetic Engineering, Noakhali Science and Technology University, Noakhali, Bangladesh.
Shuvo Chandra DasDepartment of Biotechnology and Genetic Engineering, Noakhali Science and Technology University, Noakhali, Bangladesh.
Dhirendra Nath BarmanDepartment of Biotechnology and Genetic Engineering, Noakhali Science and Technology University, Noakhali, Bangladesh.ORCID https://orcid.org/0000-0002-7086-976X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Methods: A hypothetical protein HP (PBJ89160.1) from Results: The protein is predicted to be acidic, soluble and hydrophilic by physicochemical properties analysis. Subcellular localization analysis demonstrated the protein to be periplasmic. The HP has an ATP-binding cassette transporter (also known as ABC transporter) involved in uptake of methionine (MetQ) that creates nutritional virulence in host. Energy minimization, multiple quality assessments, and validation value determination led to the conclusion that the HP model had a workable and acceptable quality. Following ADMET analysis and binding affinity assessments from the docking studies, Loperamide emerged as the most promising therapeutic compound, effectively inhibiting the ATP transporter activity of the HP. Conclusion: Comparative genomic analysis revealed that this protein is specific to

Indexed as

ABC transporter superfamilyATP-binding cassette transporterhypothetical proteinMET-Qnutritional virulence

Identifiers

PMID39534576
PMCPMC11555745

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.