Evidence map›Paper›PMID 39534366›Full record

ArticleBrain, behavior, & immunity - health2024

Associations between uric acid and depressive symptoms, and the mediating role of immunoinflammatory: Findings from rural older adults.

Yating Luo, Sha Wang, Qinqin Cheng, Jing Li, Huiyi Zhang, Jingying Wang, Juan Luo, Chen Pan, Qiuxiang Zhang, Jianfei Xie and 1 more

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In one paragraph

Article in Brain, behavior, & immunity - health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yating LuoNursing Department, The Third Xiangya Hospital, Central South University, Changsha, China.
Sha WangNursing Department, The Third Xiangya Hospital, Central South University, Changsha, China.
Qinqin ChengNursing Department, The Hunan Cancer Hospital, Changsha, China.
Jing LiXiangya School of Nursing, Central South University, Changsha, China.
Huiyi ZhangXiangya School of Nursing, Central South University, Changsha, China.
Jingying WangXiangya School of Nursing, Central South University, Changsha, China.
Juan LuoXiangya School of Nursing, Central South University, Changsha, China.
Chen PanPsychological Department, The Third Xiangya Hospital, Central South University, Changsha, China.
Qiuxiang ZhangNursing Department, The Third Xiangya Hospital, Central South University, Changsha, China.
Jianfei XieNursing Department, The Third Xiangya Hospital, Central South University, Changsha, China.
Andy S K ChengSchool of Health Sciences, Western Sydney University, Sydney, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In the low-resource rural areas, older adults may experience prolonged and severe depressive symptoms. This study aimed to investigate the relationship between uric acid, depressive symptoms and immunoinflammatory among rural older adults. Method: This case-control study was conducted in 17 rural villages in Hunan Province, China, between January 2023 and April 2024. This study included 180 participants: (1) Rural Older Adults with Depressive Symptoms group:90 patients with first-time diagnosed with depressive symptoms (Geriatric Depression Scale-15, GDS-15 ≥ 5 scores); (2) Control group: 90 individually matched (age and sex) healthy subjects (GDS-15 < 5 scores) who were aged ≥60 years. Results: Both males and females, depressive symptoms were associated with higher uric acid levels and C-reactive protein levels (All Conclusion: Further investigation is necessary to clarify the underlying mechanisms, examine gender-specific disparities, and assess potential therapeutic interventions targeting uric acid and inflammation levels to mitigate mental disorders risk.

Indexed as

Depressive symptomsImmunoinflammatoryRural older adultsUric acid

Identifiers

PMID39534366
PMCPMC11555418

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.