Evidence map›Paper›PMID 39534183›Full record

ArticleToxicology research2024

Antibiotic contaminants and their impact in Gingee River, Puducherry: insights from SPE-UPLC-MS/MS and zebrafish study.

Patharaj Gokul, Murugesan Sobanaa, S Hari Krishna Kumar, Ragothaman Prathiviraj, Rajesh Pamanji, Medapati Nikitha Lakshmi Suseela, Bhaskar Vallamkonda, Aseem Setia, Joseph Selvin, Madaswamy S Muthu

Abstract read
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In one paragraph

Article in Toxicology research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Patharaj GokulDepartment of Pharmaceutical Engineering and Technology, Indian Institute of Technology (BHU), Varanasi-221005, Uttar Pradesh, India.ORCID https://orcid.org/0009-0004-8112-2460
Murugesan SobanaaDepartment of Microbiology, Pondicherry University, Puducherry 605014, India.ORCID https://orcid.org/0000-0003-2001-6694
S Hari Krishna KumarDepartment of Microbiology, Pondicherry University, Puducherry 605014, India.ORCID https://orcid.org/0000-0001-9163-9739
Ragothaman PrathivirajDepartment of Microbiology, Pondicherry University, Puducherry 605014, India.ORCID https://orcid.org/0000-0002-4747-1374
Rajesh PamanjiDepartment of Microbiology, Pondicherry University, Puducherry 605014, India.ORCID https://orcid.org/0000-0003-3978-8301
Medapati Nikitha Lakshmi SuseelaDepartment of Pharmaceutical Engineering and Technology, Indian Institute of Technology (BHU), Varanasi-221005, Uttar Pradesh, India.ORCID https://orcid.org/0000-0003-1928-9943
Bhaskar VallamkondaDepartment of Pharmaceutical Science, School of Applied Sciences and Humanities, VIGNAN's Foundation for Science, Technology & Research, Vadlamudi, Andhra Pradesh 522213, India.ORCID https://orcid.org/0009-0004-6412-8182
Aseem SetiaDepartment of Pharmaceutical Engineering and Technology, Indian Institute of Technology (BHU), Varanasi-221005, Uttar Pradesh, India.ORCID https://orcid.org/0000-0003-0535-6260
Joseph SelvinDepartment of Microbiology, Pondicherry University, Puducherry 605014, India.ORCID https://orcid.org/0000-0001-9292-8145
Madaswamy S MuthuDepartment of Pharmaceutical Engineering and Technology, Indian Institute of Technology (BHU), Varanasi-221005, Uttar Pradesh, India.ORCID https://orcid.org/0000-0001-5805-7921

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The accumulation of antibiotic residues in ecosystems is intricately tied to the proliferation of bacterial resistance to antibiotics, with far-reaching consequences for the health and welfare of both humans and animal well-being. The analytical approach integrates solid phase extraction (SPE) with ultra performance liquid chromatography-mass spectrometry (UPLC-MS/MS) for quantification of multiclass antibiotic residues. Upon applying the aforementioned method to analyse water samples collected from the Gingee River, revealed the existence of five distinct antibiotics. This is the first study reporting antibiotic concentration in the Gingee River, Puducherry. The concentrations of nalidixic acid, sulfamethoxazole, and tetracycline were determined to be 8.5, 6.9, and 4.8 μg/L, respectively. Metronidazole and trimethoprim were detected at concentrations below the quantifiable limit. The microbial study of water samples also indicated that

Indexed as

Antibiotic contaminationAquatic ecosystem impactEnvironmental antibiotic concentrationResistance surveillanceZebrafish

Identifiers

PMID39534183
PMCPMC11551050

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.