Evidence map›Paper›PMID 39533922›Full record

ArticleOpen biology2024

The pivotal role of osteopontin in UV-induced skin inflammation in a mouse model.

Haesoo Kim, Chang-Yup Shin, Chi-Hyun Park, Dong Hun Lee, Si-Hyung Lee, Jin Ho Chung

Abstract read
In one paragraph

Article in Open biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Haesoo KimDepartment of Dermatology, Seoul National University College of Medicine, Seoul, Republic of Korea.
Chang-Yup ShinDepartment of Dermatology, Seoul National University College of Medicine, Seoul, Republic of Korea.
Chi-Hyun ParkDepartment of Dermatology, Seoul National University College of Medicine, Seoul, Republic of Korea.
Dong Hun LeeDepartment of Dermatology, Seoul National University College of Medicine, Seoul, Republic of Korea.
Si-Hyung LeeDepartment of Dermatology, Seoul National University College of Medicine, Seoul, Republic of Korea.
Jin Ho ChungDepartment of Dermatology, Seoul National University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-0582-6392

Funding

Seoul National University Hospital
6 · The paper itself

Abstract

Osteopontin (OPN) is a pro-inflammatory protein that influences bone remodelling, wound healing, angiogenesis, allergic inflammation, and skin diseases such as psoriasis, contact dermatitis and skin cancer. However, the role of OPN in the skin remains unclear. Therefore, this study aimed to investigate the role of OPN in the skin, particularly in the context of ultraviolet (UV) irradiation-induced inflammation. OPN expression and its effects on inflammatory modulators were assessed in human skin, in a mouse model and

Indexed as

Disease Models, AnimalOsteopontinSkinUltraviolet RaysAnimalsCytokinesDermatitisFibroblastsHumansInflammationKeratinocytesMiceMice, KnockoutCytokinesOsteopontininflammationosteopontinphotoagingultraviolet light

Identifiers

PMID39533922
PMCPMC11558241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.