Evidence map›Paper›PMID 39533850›Full record

ArticleInfluenza and other respiratory viruses2024

The Burden of Seasonal Influenza and Its Potential Complications Among Older Japanese Adults: A Real-World Database Study.

Takeshi Arashiro, Yuki Tajima, Yohei Ban, Matthew M Loiacono, Masayo Ideguchi, Caroline de Courville

Abstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Takeshi ArashiroVaccines Medical, Sanofi K.K., Tokyo, Japan.ORCID 0000-0002-5215-1500
Yuki TajimaMedical Affairs Real World Evidence Generation Partnering, Sanofi K.K., Tokyo, Japan.ORCID 0000-0003-3405-6136
Yohei BanReal-World Evidence Department, INTAGE Healthcare, Inc., Tokyo, Japan.
Matthew M LoiaconoMedical Evidence Generation, Sanofi, Swiftwater, Pennsylvania, USA.ORCID 0000-0001-8100-465X
Masayo IdeguchiHealth Economics and Value Assessment, Market Access, Sanofi K.K., Tokyo, Japan.
Caroline de CourvilleHealth Economics and Value Assessment, Sanofi, Lyon, France.ORCID 0000-0001-9396-6071

Funding

Sanofi K.K.
6 · The paper itself

Abstract

backgroundSeasonal influenza may lead to severe complications, including respiratory and cardiovascular disease, that result in considerable healthcare resource utilization (HCRU) and mortality, particularly in older individuals. This real-world study assessed the burden of influenza and its potential complications in older Japanese adults.

methodsThis retrospective claims database analysis (April 2015 to June 2019) included insured individuals aged ≥ 60 years at the start of four consecutive influenza seasons in Japan (October 1 to April 30). The primary endpoint was the incidence of influenza-related emergency room (ER) and outpatient visits, the incidence of hospitalizations, the probability of 30-day inpatient mortality, and 60-day medical costs of influenza or its potential complications.

resultsOf 8,974,708 individuals (43.2% male, mean ± standard deviation age 73.8 ± 8.9 years), 370,430 (4.13%) were diagnosed with influenza. Overall, 17.18 (95% confidence interval [CI] 16.32-18.04) and 3893.53 (3880.87-3906.19) per 100,000 individuals had influenza-related ER and outpatient visits, respectively, and 181.50 (178.71-184.28) per 100,000 individuals were hospitalized for influenza. The incidence of influenza-related ER visits and hospitalizations for influenza or potential complications and the probability of 30-day inpatient mortality increased with age.

conclusionsSeasonal influenza and its potential complications represent a substantial burden that increases with age in Japanese individuals.

Indexed as

Databases, FactualHospitalizationInfluenza, HumanSeasonsAgedAged, 80 and overCost of IllnessEast Asian PeopleFemaleHumansIncidenceJapanMaleMiddle AgedRetrospective Studiesagedhealthcare costshospitalizationhumaninfluenzaJapanmortality

Identifiers

PMID39533850
PMCPMC11557991

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.