Evidence map›Paper›PMID 39533706›Full record

ArticleMolecular pharmaceutics2024

Immuno-PET Imaging of CD93 Expression with

Xiaoyan Li, Wenyu Song, Jonathan W Engle, Jason C Mixdorf, Todd E Barnhart, Yi Sun, Yuwen Zhu, Weibo Cai

Abstract read
In one paragraph

Article in Molecular pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaoyan LiDepartments of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.ORCID 0009-0000-3325-5366
Wenyu SongDepartment of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
Jonathan W EngleDepartments of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.ORCID 0000-0002-3399-7228
Jason C MixdorfDepartments of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.
Todd E BarnhartDepartments of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.
Yi SunDepartment of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045, United States.
Yuwen ZhuDepartment of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045, United States.
Weibo CaiDepartments of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.ORCID 0000-0003-4641-0833

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Justine Yang Bruce · 1985 to 2026
$142.6M
The CD93 pathway and melanoma therapyR01CA258302 · NCI · UNIVERSITY OF COLORADO DENVER · PI Yuwen Zhu · 2022 to 2026
$1.8M
Melanoma Immunotherapy with GPR182 blockadeR01CA269644 · NCI · UNIVERSITY OF COLORADO DENVER · PI Yuwen Zhu · 2023 to 2026
$1.4M
The GPR171 pathway in cancer immunotherapyR01CA279398 · NCI · UNIVERSITY OF COLORADO DENVER · PI Yuwen Zhu · 2023 to 2026
$1.4M
NCI NIH HHS P30 CA014520NCI NIH HHS R01 CA258302NCI NIH HHS R01 CA269644NCI NIH HHS R01 CA279398
6 · The paper itself

Abstract

CD93 is overexpressed in multiple solid tumor types, serving as a novel target for antiangiogenic therapy. The goal of this study was to develop a

Indexed as

Copper RadioisotopesHeterocyclic CompoundsInsulin-Like Growth Factor Binding ProteinsPositron-Emission TomographyAnimalsAntibodies, MonoclonalBreast NeoplasmsCell Line, TumorFemaleGPI-Linked ProteinsHeterocyclic Compounds, 1-RingHumansMiceMice, NudeRadiopharmaceuticalsTissue Distribution1,4,7-triazacyclononane-N,N',N''-triacetic acidAntibodies, MonoclonalCopper-64Copper RadioisotopesGPI-Linked ProteinsHeterocyclic CompoundsHeterocyclic Compounds, 1-Ringinsulin-like growth factor binding protein-related protein 1Insulin-Like Growth Factor Binding ProteinsRadiopharmaceuticals64CuCD93 pathwayImmunoPETinsulin-like growth factor binding protein 7 (IGFBP7)tumor angiogenesisvascular endothelial growth factor (VEGF)

Identifiers

PMID39533706
PMCPMC11832137

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.