Evidence map›Paper›PMID 39533704›Full record

ArticleScandinavian journal of primary health care2025

Exploring participants' characteristics and self-assessed readiness to conduct clinical trials in general practice - baseline analysis of the RaPHaeL practice-based research network.

Alexander Bauer, Larissa Virnau, Eric Sven Kroeber, Heidrun Lingner, Markus Bleckwenn, Thomas Frese, Kathleen Denny, Annett Braesigk, Tobias Deutsch

Abstract read
In one paragraph

Article in Scandinavian journal of primary health care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexander BauerInstitute of General Practice and Family Medicine, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.ORCID 0000-0001-5262-4315
Larissa VirnauCentre for Public Health and Healthcare, Hannover Medical School, Hannover, Germany.
Eric Sven KroeberInstitute of General Practice and Family Medicine, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.
Heidrun LingnerCentre for Public Health and Healthcare, Hannover Medical School, Hannover, Germany.ORCID 0000-0003-2074-0367
Markus BleckwennInstitute of General Practice, Faculty of Medicine, University of Leipzig, Leipzig, Germany.ORCID 0000-0003-1975-5369
Thomas FreseInstitute of General Practice and Family Medicine, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.
Kathleen DennyInstitute of General Practice and Family Medicine, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.
Annett BraesigkInstitute of General Practice, Faculty of Medicine, University of Leipzig, Leipzig, Germany.ORCID 0000-0002-1601-3442
Tobias DeutschInstitute of General Practice, Faculty of Medicine, University of Leipzig, Leipzig, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrimary care is integral to healthcare systems extending beyond traditional illness management to include preventive care, chronic disease management, and health promotion. Practice-based research networks (PBRNs) have emerged as essential infrastructures for conducting clinical research in primary care. This study explores the establishment of the 'Research-Practices Halle-Leipzig' (RaPHaeL) PBRN in Germany, evaluating the characteristics and research readiness of participating practices.

methodsA cross-sectional survey (MORNING II) was conducted among all general practitioners (GPs) joining the RaPHaeL PBRN, assessing socio-demographic characteristics, practice infrastructure, and research readiness. After a descriptive analysis, we compared data with a previous study (MORNING) to examine potential differences between PBRN participants and non-participants. We developed a research readiness score (RRS) to quantify practices' ability to perform clinical research subtasks.

resultsThe response rate was 97.1% and our participants were often male, involved in undergraduate education, generally interested in research or had previous research experiences. However, they differed widely in age and size, staff structure, and patient demographics of their practices. Initially, around two-thirds of the practices were not sufficiently prepared to conduct clinical trials (self-assessed feasibility of relevant subtasks). If further research and documentation tasks are required, patient recruitment estimations are lower than for patient identification and information.

conclusionThis study highlights the variability in research readiness among GP practices and shows the need for targeted training. By systematically assessing and enhancing research capabilities of participating GPs, PBRNs can facilitate high-quality clinical research in primary care to improve patient outcomes and healthcare delivery.

Indexed as

Attitude of Health PersonnelClinical Trials as TopicGeneral PracticeGeneral PractitionersPrimary Health CareAdultCross-Sectional StudiesFemaleGermanyHumansMaleMiddle AgedSurveys and Questionnairesclinical researchfamily medicinegeneral practicehealth services researchPractice-based research networks (PBRN)primary health careresearch readiness

Identifiers

PMID39533704
PMCPMC12090295

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.