Evidence map›Paper›PMID 39533414›Full record

ArticlePilot and feasibility studies2024

Comparison of 45-min nap versus no-nap during simulated night shift work on endothelial function: a randomized crossover feasibility trial.

P Daniel Patterson, Cassie J Hilditch, Sarah E Martin, David G L Roach, Matthew D Weaver, Tiffany S Okerman, David Hostler, Leonard S Weiss, Steven E Reis

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pilot and feasibility studies, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05436951 (Night Shift Work, On-shift Napping, and Endothelial Function), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05436951 nacompletednot on this map

Night Shift Work, On-shift Napping, and Endothelial Function: A Pilot Study

TypeinterventionalSponsorUniversity of PittsburghRan2022 to 2023Enrolled10ConditionsBlood Pressure, Endothelial DysfunctionArmsBrief on-shift nap
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

P Daniel PattersonDepartment of Emergency Medicine, School of Medicine, University of Pittsburgh, PA, Pittsburgh, 15261, USA. pdp3@pitt.edu.
Cassie J HilditchFatigue Countermeasures Laboratory, San José State University, CA, San José, 95192, USA.
Sarah E MartinDepartment of Emergency Medicine, School of Medicine, University of Pittsburgh, PA, Pittsburgh, 15261, USA.
David G L RoachDepartment of Emergency Medicine, School of Medicine, University of Pittsburgh, PA, Pittsburgh, 15261, USA.
Matthew D WeaverDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital, MA, Boston, 02115, USA.
Tiffany S OkermanDepartment of Emergency Medicine, School of Medicine, University of Pittsburgh, PA, Pittsburgh, 15261, USA.
David HostlerDepartment of Exercise and Nutrition Sciences, School of Public Health and Health Professions, University at Buffalo, NY, Buffalo, 14214, USA.
Leonard S WeissDepartment of Emergency Medicine, School of Medicine, University of Pittsburgh, PA, Pittsburgh, 15261, USA.
Steven E ReisDepartment of Medicine, University of Pittsburgh, PA, Pittsburgh, 15261, USA.

Funding

Department of Emergency Medicine, University of Pittsburgh None provided
6 · The paper itself

Abstract

backgroundNight shift workers face increased risk of cardiovascular disease (CVD) compared to non-shift workers. Evidence supports on-shift napping and regular non-invasive monitoring of endothelial function for risk mitigation, yet neither strategy is widely used.

methodsWe evaluated the feasibility of non-invasive assessment of peripheral arterial tone (PAT) to assess the effect of napping during simulated night shift work on endothelial function. We used a single-site, randomized crossover trial of simulated night shift work with a 45-min nap condition versus a control, no-nap condition (ClinicalTrials.gov NCT05436951).

resultsThe primary outcome was the number of participants with ≥ 70% of endothelial function assessments. Secondary outcomes included mean reactive hyperemia index (RHI), BP, and cognitive performance with the brief psychomotor vigilance task (PVT-B). Of the 10 consented, 9 completed both conditions. All participants exceeded feasibility benchmarks. Mean RHI did not differ by nap condition, and the delta from pre- to post measure did not differ (difference in delta =  - 0.26, 95% CI - 1.09, 0.58). Hourly PVT-B assessments from 19:00 to 07:00 h did not differ by nap condition. Compared to pre-nap measures, cognitive performance on the PVT-B was poorest at + 0 min post-nap.

conclusionOur findings can inform larger studies evaluating the effects of night shift work and napping on endothelial function. TRIAL REGISTRATIONS: ClinicalTrials.gov (NCT05436951, registered on June 23, 2022).

Indexed as

Cardiovascular diseaseEndothelial functionNappingNight shift workSleep

Identifiers

PMID39533414
PMCPMC11555913

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.