Evidence map›Paper›PMID 39533383›Full record

ArticleJournal of medical case reports2024

Surgical versus non-surgical management of hyperfunctional thyroid metastasis: a case report.

Athena Farahzadi, Fatemeh Moosaie, Seyed Mohammad Tavangar, Hojat Ebrahiminik, Sepide Javankiani, Hossein Chegeni, Mohammad Shirkhoda

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Athena Farahzadi *Department of General Surgery, Subdivision of Surgical Oncology, Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Imam Khomeini Hospital Complex, Dr. Qarib St, Keshavarz Blvd, P.O Box: 1419733141, Tehran, Iran.
Fatemeh Moosaie *Department of General Surgery, Subdivision of Surgical Oncology, Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Imam Khomeini Hospital Complex, Dr. Qarib St, Keshavarz Blvd, P.O Box: 1419733141, Tehran, Iran.
Seyed Mohammad TavangarDepartment of Pathology, Dr. Shariati Hospital, Tehran University of Medical Sciences, Chronic Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Hojat EbrahiminikDepartment of Interventional Radiology and Radiation, Sciences Research Center, AJA University of Medical Sciences, Etemadzadeh St., West Fatemi St., Tehran, Tehran Province, Iran.
Sepide JavankianiDepartment of General Surgery, Subdivision of Surgical Oncology, Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Imam Khomeini Hospital Complex, Dr. Qarib St, Keshavarz Blvd, P.O Box: 1419733141, Tehran, Iran.
Hossein ChegeniDepartment of Interventional Radiology and Radiation, Sciences Research Center, AJA University of Medical Sciences, Etemadzadeh St., West Fatemi St., Tehran, Tehran Province, Iran.
Mohammad ShirkhodaDepartment of General Surgery, Subdivision of Surgical Oncology, Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Imam Khomeini Hospital Complex, Dr. Qarib St, Keshavarz Blvd, P.O Box: 1419733141, Tehran, Iran. mshirkhoda@sina.tums.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHyperthyroidism, caused by metastatic differentiated thyroid cancer, is a rare condition that can be difficult to diagnose. Thyrotoxicosis and metastatic disease regarding functional metastasis increase morbidity and mortality in patients with functional metastasis and need to be treated. This study aims to present a case of hyper-functional metastasis of thyroid cancer to analyze its pathological features, diagnostic procedures, and treatment options and to gather and examine recent cases of hyper-functional metastasis of thyroid cancer. CASE PRESENTATION: A 26-year-old Iranian woman presenting with hyperthyroidism and a solid cystic nodule measuring 14.5 × 15.7 × 19.6 mm in the left thyroid lobe underwent thyroid surgery revealing papillary thyroid carcinoma. Despite lymph node metastasis, she refused further surgery and opted for lymph node radiofrequency ablation and radioactive iodine therapy. Subsequent follow-ups showed no recurrence of lymphadenopathy, normalized thyroid function, and decreasing triglyceride levels, with the patient under surveillance.

conclusionRadioactive iodine is a first-line treatment option for patients with hyperactive thyroid cancer presenting with metastatic disease. Another therapeutic option is surgery, which is performed to maximize the reduction of thyroid tissue, lymph nodes, and distant metastasis.

Indexed as

Iodine RadioisotopesThyroid Cancer, PapillaryThyroidectomyThyroid NeoplasmsAdultFemaleHumansHyperthyroidismLymphatic MetastasisRadiofrequency AblationTreatment OutcomeIodine RadioisotopesCase reportHyperfunctioning thyroid carcinomaMetastasisThyroid carcinomaThyrotoxicosis

Identifiers

PMID39533383
PMCPMC11558896

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.