Trial reportBMC health services research2024
Strategies for implementing an electronic patient-reported outcomes-based symptom management program across six cancer centers.
Trial report in BMC health services research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03850912 (SIMPRO Research Center), which is not on this map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
SIMPRO Research Center: Integration and Implementation of PROs for Symptom Management in Oncology Practice
Who cites it
11 citing papers in PubMed.
- Quality of life during electronic patient-reported outcome (ePRO) monitoring in thoracic surgery patients: a pilot randomized controlled trial.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Trial
- Implementation outcomes of a symptom management intervention in ambulatory oncology practices evaluated using a cluster randomized stepped-wedge trial design.Implementation science : IS · 2025Trial
- Cost-Effective Components of a Patient-Reported Symptom Monitoring System for Chemotherapy.JAMA network open · 2025Trial
- Mixed-Methods User-Centered Design Evaluation of an Electronic Patient-Reported Outcomes System to Enhance Postdischarge Care for Thoracic Surgery Patients.The Journal of surgical research · 2026Article
- Staff Perspectives on Normalizing and Sustaining Electronic Patient-Reported Outcomes Monitoring at Six US Health Systems.JCO oncology practice · 2026Article
- Perioperative EGFR-Targeted Therapy in Resectable EGFR-Mutated NSCLC: A Narrative Review from Drug Design to Pain-Informed MRD-Guided Care.Drug design, development and therapy · 2026Review
- Does Electronic Symptom Monitoring Improve Symptom Burden and Self-Efficacy Among Chemotherapy and Surgery Patients Across Six Cancer Centers?JCO oncology practice · 2025Article
- Optimizing Patient Engagement with Patient-Reported Outcome Measures Across the Cancer Continuum: A Qualitative Study.Palliative medicine reports · 2025Article
- Using Electronic Patient-Reported Outcome Monitoring to Navigate Patients to Supportive Care Services.JCO oncology practice · 2024Article
- Using Quality Improvement and Implementation Science to Identify Strategies That Foster Electronic Patient-Reported Outcome Submissions.Journal for healthcare quality : official publication of the National Association for Healthcare QualityArticle
- Article
Corrections and comments
- Update of
Authors and funding
17 authors.
Funding
Abstract
backgroundElectronic patient-reported outcome (ePRO)-based symptom management improves cancer patients' outcomes. However, implementation of ePROs is challenging, requiring technical resources for integration into clinical systems, substantial buy-in from clinicians and patients, novel workflows to support between-visit symptom management, and institutional investment.
methodsThe SIMPRO Research Consortium developed eSyM, an electronic health record-integrated, ePRO-based symptom management program for medical oncology and surgery patients and deployed it at six cancer centers between August 2019 and April 2022 in a type II hybrid effectiveness-implementation cluster randomized stepped-wedge study. Sites documented implementation strategies monthly using REDCap, itemized them using the Expert Recommendations for Implementation Change (ERIC) list and mapped their target barriers using the Consolidated Framework for Implementation Research (CFIR) to inform eSyM program enhancement, facilitate inter-consortium knowledge sharing and guide future deployment efforts.
resultsWe documented 226 implementation strategies: 35 'foundational' strategies were applied consortium-wide by the coordinating center and 191 other strategies were developed by individual sites. We consolidated these 191 site-developed strategies into 64 unique strategies (i.e., removed duplicates) and classified the remainder as either 'universal', consistently used by multiple sites (N = 29), or 'adaptive', used only by individual sites (N = 35). Universal strategies were perceived as having the highest impact; they addressed eSyM clinical preparation, training, engagement of patients/clinicians, and program evaluation. Across all documented SIMPRO strategies, 44 of the 73 ERIC strategies were addressed and all 5 CFIR barriers were addressed.
conclusionMethodical collection of theory-based implementation strategies fostered the identification of universal, high-impact strategies that facilitated adoption of a novel care-delivery intervention by patients, clinicians, and institutions. Attention to the high-impact strategies identified in this project could support implementation of ePROs as a component of routine cancer care at other institutions.
trial registrationClinicalTrials.gov. NCT03850912. February 22, 2019. https://clinicaltrials.gov/ct2/show/NCT03850912?term=hassett&draw=2&rank=1.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.