Evidence map›Paper›PMID 39533207›Full record

ArticleBMC ophthalmology2024

A clinical study on the therapeutic effects of 577 nm micropulse laser photocoagulation treatment in early-stage CSCR patients.

Hao Wang, Dengli Zhao, Li Ran, Sha Li, Yanling Long, Min Wang, Linbo He, Yong Liu

Abstract read
In one paragraph

Article in BMC ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hao Wang *Southwest Hospital/Southwest Eye Hospital, Army Medical University, Chongqing, China.
Dengli Zhao *Southwest Hospital/Southwest Eye Hospital, Army Medical University, Chongqing, China.
Li RanSouthwest Hospital/Southwest Eye Hospital, Army Medical University, Chongqing, China. pmlz0214@163.com.
Sha LiSouthwest Hospital/Southwest Eye Hospital, Army Medical University, Chongqing, China.
Yanling LongSouthwest Hospital/Southwest Eye Hospital, Army Medical University, Chongqing, China.
Min WangSouthwest Hospital/Southwest Eye Hospital, Army Medical University, Chongqing, China.
Linbo HeSouthwest Hospital/Southwest Eye Hospital, Army Medical University, Chongqing, China.
Yong LiuSouthwest Hospital/Southwest Eye Hospital, Army Medical University, Chongqing, China. liuyong@tmmu.edu.cn.

Funding

National Natural Science Foundation of China 81900902National Natural Science Foundation of China 81970843
6 · The paper itself

Abstract

purposeTo research the therapeutic effects of 577 nm micropulse laser photocoagulation (MLP) treatment in early-stage central serous chorioretinopathy (CSCR) patients.

methodsTwenty-two CSCR patients with 24 CSCR eyes were examined prior to MLP treatment. The examinations included best-corrected visual acuity (BCVA), fluorescein fundus angiography (FFA), indocyanine green angiography (ICGA), optical coherence tomography (OCT), optical coherence tomography angiography (OCTA) and microperimetry. After MLP treatment, all the subjects were reviewed at 30 days. The BCVA, macular function on microperimetry, subretinal fluid (SRF) height of the macula on OCT, and choroid vascular density (VD) of the macular area on OCTA were compared before and after MLP treatment. The correlations between SRF height and visual function, choroid VD was analyzed separately.

resultsBCVA and macular function significantly increased and the SRF height of the macula significantly decreased after MLP treatment. BCVA and macular function were significantly negatively correlated with SRF height. The choroid VD was significantly increased after MLP treatment, and choroid VD in the leakage site part of the macula were significantly negatively correlated with the height of the SRF. A recurrent patient who received two MLP treatments also had a negative correlation between SRF and choroid VD during the course of disease.

conclusions577 nm MLP is safe and effective for early-stage CSCR patients, and treatment can restore macular structure and function. The increase in choroid VD of leakage site part after treatment is one of the key effects of MLP treatment for early-stage CSCR patients.

Indexed as

Central Serous ChorioretinopathyFluorescein AngiographyLaser CoagulationTomography, Optical CoherenceVisual AcuityAdultChoroidFemaleFundus OculiHumansMacula LuteaMaleMiddle AgedTreatment Outcome577 nm micropulse laser photocoagulationCentral serous chorioretinopathyChoroid vascular densitySubretinal fluid heightVisual function

Identifiers

PMID39533207
PMCPMC11558810

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.