Evidence map›Paper›PMID 39532602›Full record

ArticleTrends in pharmacological sciences2024

Some assembly required: a single-RNA vaccine against enterovirus-D68.

Noah Pollack, William T Jackson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Trends in pharmacological sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Noah PollackDepartment of Microbiology and Immunology and Center for Pathogen Research, University of Maryland School of Medicine, 685 W. Baltimore Avenue, Baltimore, MD 21201, USA.
William T JacksonDepartment of Microbiology and Immunology and Center for Pathogen Research, University of Maryland School of Medicine, 685 W. Baltimore Avenue, Baltimore, MD 21201, USA. Electronic address: wjackson@som.umaryland.edu.

Funding

Signaling Pathways in Innate ImmunityT32AI095190 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI Stefanie N. Vogel · 2012 to 2026
$4.7M
The roles of acidic autophagosomes in production of infectious poliovirusR01AI104928 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI JACKSON, WILLIAM T · 2014 to 2023
$3.8M
Enterovirus manipulation of autophagic trafficking pathwaysR01AI141359 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI JACKSON, WILLIAM T · 2019 to 2022
$1.5M
Immune Response Regulation by virusesF32HL067557 · NHLBI · STANFORD UNIVERSITY · PI JACKSON, WILLIAM T · 2001 to 2003
$127k
NHLBI NIH HHS F32 HL067557NIAID NIH HHS R01 AI104928NIAID NIH HHS R01 AI141359NIAID NIH HHS T32 AI095190
6 · The paper itself

Abstract

A single-RNA-based vaccine against enterovirus-D68, a respiratory virus and causative agent of severe paralytic disease in children, by the Erasmus group shows great promise in generating broadly cross-neutralizing antibodies in mice and macaque models of infection.

Indexed as

Enterovirus D, HumanEnterovirus InfectionsViral VaccinesAnimalsAntibodies, NeutralizingHumansMicemRNA VaccinesAntibodies, NeutralizingmRNA VaccinesViral Vaccinesacute flaccid myelitisenterovirus D68RNA vaccinevirus-like particles

Identifiers

PMID39532602
PMCPMC11624984

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.