Evidence map›Paper›PMID 39531318›Full record

ArticleKidney3602025

Macrophage-Specific Lactate Dehydrogenase Expression Modulates Inflammatory Function In Vitro.

Yan Lu, Gunars Osis, Anna A Zmijewska, Amie Traylor, Saakshi Thukral, Landon Wilson, Stephen Barnes, James F George, Anupam Agarwal

Abstract read
In one paragraph

Article in Kidney360, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Glycolytic reprogramming in host response toExperimental and therapeutic medicine · 2026
    Article
  4. Article
  5. ST2 Signaling Regulates Innate Immune Responses in Kidney Injury.bioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yan LuDivision of Nephrology, Department of Medicine, Nephrology Research and Training Center, University of Alabama at Birmingham, Birmingham, Alabama.
Gunars OsisDivision of Nephrology, Department of Medicine, Nephrology Research and Training Center, University of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0002-0613-737
Anna A ZmijewskaDivision of Nephrology, Department of Medicine, Nephrology Research and Training Center, University of Alabama at Birmingham, Birmingham, Alabama.
Amie TraylorDivision of Nephrology, Department of Medicine, Nephrology Research and Training Center, University of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0001-7867-0096
Saakshi ThukralDivision of Nephrology, Department of Medicine, Nephrology Research and Training Center, University of Alabama at Birmingham, Birmingham, Alabama.
Landon WilsonDepartment of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, Alabama.
Stephen BarnesDepartment of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0001-6837-1674
James F GeorgeDepartment of Surgery, University of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0003-0325-7891
Anupam AgarwalDivision of Nephrology, Department of Medicine, Nephrology Research and Training Center, University of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0003-4276-5186

Funding

UAB Research Center of Excellence in ArsenicalsU54ES030246 · NIEHS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ATHAR, MOHAMMAD · 2018 to 2022
$19.0M
Human Heme Oxygenase-1 Gene Regulation in Renal InjuryR01DK059600 · NIDDK · UNIVERSITY OF FLORIDA · PI AGARWAL, ANUPAM, GEORGE, JAMES F · 2002 to 2019
$4.5M
UAB-UCSD O'Brien Center for Acute Kidney Injury ResearchU54DK137307 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI PAUL W. SANDERS · 2023 to 2026
$4.4M
Mononuclear phagocytes in the pathogenesis of acute kidney injuryR01DK118932 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AGARWAL, ANUPAM, GEORGE, JAMES F · 2019 to 2023
$2.3M
5500 Q-Trap Mass SpectrometerS10RR027822 · NCRR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARNES, STEPHEN · 2010 to 2010
$469k
American Heart Association 20PRE35200054NCRR NIH HHS S10 RR027822NIDDK NIH HHS DK118932NIDDK NIH HHS DK59600NIDDK NIH HHS R01 DK059600NIDDK NIH HHS R01 DK118932NIDDK NIH HHS U54 DK137307NIEHS NIH HHS U54 ES030246NIH HHS S10 RR027822University of Alabama at Birmingham Frommeyer Fellowship Award
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39531318
PMCPMC11882262

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.