Evidence map›Paper›PMID 39531201›Full record

ReviewCurrent topics in behavioral neurosciences2025

Interoception, Insula, and Autonomic Integration: Relevance to the Expression and Treatment of Psychiatric Symptoms.

Hugo D Critchley, Joel Patchitt

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current topics in behavioral neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. The Human Insula Reimagined: Single Neurons Respond to Simple Sounds during Passive Listening.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  4. Human insula neurons respond to simple sounds during passive listening.bioRxiv : the preprint server for biology · 2025
    Article
  5. The Intersection of Interoception and Anticipation Related to Pain.Current topics in behavioral neurosciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hugo D CritchleyDepartment of Clinical Neuroscience, Brighton and Sussex Medical School, University of Sussex, Brighton, UK. h.critchley@bsms.ac.uk.ORCID https://orcid.org/0000-0002-2445-9284
Joel PatchittDepartment of Clinical Neuroscience, Brighton and Sussex Medical School, University of Sussex, Brighton, UK.ORCID https://orcid.org/0000-0002-4662-739X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mind is embodied, and this is relevant to mental health and psychiatric illness. Interoception is the body-to-brain axis of sensory information flow and its representation at the neural and psychological levels. Interoception is the purported basis for motivation and emotion, and as an inescapable stream of information about the health and functioning of the whole organism, it is proposed to be the foundation to the conscious unitary sense of self. Correspondingly, this central representation of internal state is relevant to understanding the expression of psychological symptoms and behaviours and ultimately psychiatric disorders. Here we review interoception, particularly from a cardiovascular perspective, and how understanding theoretical neural and psychological aspects of interoception relates to perceptions, thoughts, and feelings. We examine how perturbations in interoceptive processing are expressed in mental symptoms and psychiatric disorders and show how this knowledge may yield new treatment targets.

Indexed as

Autonomic Nervous SystemInsular CortexInteroceptionMental DisordersEmotionsHumansAnxietyArousalAutismAutonomicBaroreceptorBiobehaviouralBiofeedbackCardiacCravingDissociationInteroceptionPsychiatryTherapy

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.