Evidence map›Paper›PMID 39531055›Full record

ArticleAnnals of hematology2025

Mixed-phenotype leukemia with TCF3::ZNF384 fusion presenting as an isolated mediastinal mass.

Wing-Yan Au, Chit Chow, Ka-Fai To, Edmond S K Ma, Eugene C L Yeung, Wai-Lun Yip, Helen M H Chan, Harinder Gill

Abstract readCase ReportsLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of hematology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wing-Yan AuBlood-Med Clinic, Central, Hong Kong.
Chit ChowDepartment of Anatomical and Cellular Pathology, the Chinese University of Hong Kong, Ma Liu Shui, Hong Kong.
Ka-Fai ToDepartment of Anatomical and Cellular Pathology, the Chinese University of Hong Kong, Ma Liu Shui, Hong Kong.
Edmond S K MaDepartment of Clinical and Molecular Pathology, Hong Kong Sanatorium and Hospital, Happy Valley, Hong Kong.
Eugene C L YeungEthics First Medical Practice HK, Harbour City, Hong Kong.
Wai-Lun YipDepartment of Pathology, the Hong Kong Baptist Hospital, Kowloon Tong, Hong Kong.
Helen M H ChanDepartment of Medicine, Union Hospital, Tai Wai, Hong Kong.
Harinder GillDepartment of Medicine, School of Clinical Medicine, LKS Faculty of Medicine, the University of Hong Kong, Pok Fu Lam, Hong Kong. gillhsh@hku.hk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute leukemia with TCF3::ZNF384 is a distinct type of acute leukemia that present most commonly as B-acute lymphoblastic leukemia or mixed-phenotype acute leukemia (B/myeloid). We report the first case of TCF3::ZNF384 mixed-phenotype leukemia presenting as isolated extramedullary disease in the mediastinum. Diagnosis using RNA-sequencing and whole genome sequencing on the primary issue is illustrated.

Indexed as

Leukemia, Biphenotypic, AcuteMediastinal NeoplasmsOncogene Proteins, FusionAdultBasic Helix-Loop-Helix ProteinsHumansMaleBasic Helix-Loop-Helix ProteinsOncogene Proteins, FusionTCF3 protein, humanMixed-phenotype leukemiaMyeloid sarcomaRNA-sequencingTCF3::ZNF384Whole genome sequencing

Identifiers

PMID39531055
PMCPMC12031752

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.