Evidence map›Paper›PMID 39530666›Full record

ArticleJournal of virology2024

SRCAP is involved in porcine reproductive and respiratory syndrome virus activated Notch signaling pathway.

Guofei Ding, Yingchao Li, Dexin Li, Mingyu Dou, Chaolun Fu, Ting Chen, Xinyu Cui, Qin Zhang, Pingping Yang, Yanmeng Hou and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Guofei Ding *Department of Fundamental Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Tai'an, Shandong, China.
Yingchao Li *Department of Fundamental Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Tai'an, Shandong, China.
Dexin LiDepartment of Fundamental Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Tai'an, Shandong, China.
Mingyu DouDepartment of Fundamental Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Tai'an, Shandong, China.
Chaolun FuDepartment of Fundamental Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Tai'an, Shandong, China.
Ting ChenDepartment of Fundamental Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Tai'an, Shandong, China.
Xinyu CuiDepartment of Fundamental Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Tai'an, Shandong, China.
Qin ZhangDepartment of Fundamental Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Tai'an, Shandong, China.
Pingping YangDepartment of Fundamental Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Tai'an, Shandong, China.
Yanmeng HouDepartment of Fundamental Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Tai'an, Shandong, China.
Sidang LiuDepartment of Fundamental Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Tai'an, Shandong, China.
Yihong XiaoDepartment of Fundamental Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Tai'an, Shandong, China.ORCID 0000-0002-0857-8080

Funding

MOST | National Key Research and Development Program of China (NKPs) 2022YFD1800300MOST | National Natural Science Foundation of China (NSFC) 32072818, 31772708
6 · The paper itself

Abstract

Porcine reproductive and respiratory syndrome viru IMPORTANCE: In the present study, the interactome of the NSP4 originating from PRRSV was studied and SRCAP was confirmed as one of the interactors. Mechanism study showed the interaction of Nsp4 and SRCAP was found to facilitate PRRSV infection by activating non-canonical Notch signaling. ATPase Ⅰ-Ⅳ domain in SRCAP and the

Indexed as

Porcine Reproductive and Respiratory SyndromePorcine respiratory and reproductive syndrome virusReceptors, NotchSignal TransductionViral Nonstructural ProteinsAnimalsCell LineHEK293 CellsHumansProteomicsSwineReceptors, NotchViral Nonstructural Proteinsantiviral druginteractionsnon-canonical Notch signalingnon-structural protein 4porcine reproductive and respiratory syndrome virusSRCAP

Identifiers

PMID39530666
PMCPMC11650989

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.