Evidence map›Paper›PMID 39530598›Full record

ArticleGenetics2025

Saccharomyces Genome Database: advances in genome annotation, expanded biochemical pathways, and other key enhancements.

Stacia R Engel, Suzi Aleksander, Robert S Nash, Edith D Wong, Shuai Weng, Stuart R Miyasato, Gavin Sherlock, J Michael Cherry

Abstract read
In one paragraph

Article in Genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. A multispecies toolkit ofProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. The power of many: when genetics met yeasts and high-throughput.Biological reviews of the Cambridge Philosophical Society · 2026
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

  • Update of
    2024
5 · Who and what money

Authors and funding

8 authors.

Stacia R EngelDepartment of Genetics, Stanford University, 3165 Porter Dr, Palo Alto, CA 94304, USA.ORCID 0000-0001-5472-917X
Suzi AleksanderDepartment of Genetics, Stanford University, 3165 Porter Dr, Palo Alto, CA 94304, USA.
Robert S NashDepartment of Genetics, Stanford University, 3165 Porter Dr, Palo Alto, CA 94304, USA.
Edith D WongDepartment of Genetics, Stanford University, 3165 Porter Dr, Palo Alto, CA 94304, USA.ORCID 0000-0001-9799-5523
Shuai WengDepartment of Genetics, Stanford University, 3165 Porter Dr, Palo Alto, CA 94304, USA.ORCID 0000-0003-4233-0772
Stuart R MiyasatoDepartment of Genetics, Stanford University, 3165 Porter Dr, Palo Alto, CA 94304, USA.
Gavin SherlockDepartment of Genetics, Stanford University, 3165 Porter Dr, Palo Alto, CA 94304, USA.ORCID 0000-0002-1692-4983
J Michael CherryDepartment of Genetics, Stanford University, 3165 Porter Dr, Palo Alto, CA 94304, USA.ORCID 0000-0001-9163-5180

Funding

Text mining in the CloudU24HG010859 · NHGRI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI CAROL J BULT, PAUL Warren STERNBERG · 2019 to 2026
$42.0M
Resource ProjectU41HG002273 · NHGRI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI THOMAS, PAUL D. · 2012 to 2021
$34.7M
Genomic Resource for the Yeast SaccharomycesU41HG001315 · NHGRI · STANFORD UNIVERSITY · PI CHERRY, J. MICHAEL · 2011 to 2020
$26.4M
Gene Ontology Consortium and KnowledgebaseU24HG012212 · NHGRI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHRISTOPHER J MUNGALL, PAUL Warren STERNBERG · 2022 to 2026
$11.6M
Genomic Resource for the Yeast SaccharomycesU24HG001315 · NHGRI · STANFORD UNIVERSITY · PI Stacia Engel, Gavin J Sherlock · 2021 to 2026
$10.9M
Alliance of Genome Resources U24HG010859)Gene Ontology Consortium U41HG002273)NHGRI NIH HHS U24 HG001315NHGRI NIH HHS U24 HG010859NHGRI NIH HHS U24 HG012212NHGRI NIH HHS U41 HG001315NHGRI NIH HHS U41HG001315NHGRI NIH HHS U41 HG002273US National Institutes of Health
6 · The paper itself

Abstract

Budding yeast (Saccharomyces cerevisiae) is the most extensively characterized eukaryotic model organism and has long been used to gain insight into the fundamentals of genetics, cellular biology, and the functions of specific genes and proteins. The Saccharomyces Genome Database (SGD) is a scientific resource that provides information about the genome and biology of S. cerevisiae. For more than 30 years, SGD has maintained the genetic nomenclature, chromosome maps, and functional annotation for budding yeast along with search and analysis tools to explore these data. Here, we describe recent updates at SGD, including the 2 most recent reference genome annotation updates, expanded biochemical pathway representation, changes to SGD search and data files, and other enhancements to the SGD website and user interface. These activities are part of our continuing effort to promote insights gained from yeast to enable the discovery of functional relationships between sequence and gene products in fungi and higher eukaryotes.

Indexed as

Databases, GeneticGenome, FungalMolecular Sequence AnnotationSaccharomyces cerevisiaebudding yeastknowledgebaseMODmodel organism databaseSaccharomyces cerevisiaeSGD

Identifiers

PMID39530598
PMCPMC11912841

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.