Evidence map›Paper›PMID 39530093›Full record

ArticleFrontiers in immunology2024

A minority of proliferating human CD4

Pushpak Bhattacharjee, Miha Pakusch, Matthew Lacorcia, Chris Y Chiu, Xin Liu, Eleonora Tresoldi, Abby Foster, Laura King, Fergus J Cameron, Stuart I Mannering

Abstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Pushpak BhattacharjeeImmunology and Diabetes Unit, St. Vincent's Institute of Medical Research, Melbourne, VIC, Australia.
Miha PakuschImmunology and Diabetes Unit, St. Vincent's Institute of Medical Research, Melbourne, VIC, Australia.
Matthew LacorciaImmunology and Diabetes Unit, St. Vincent's Institute of Medical Research, Melbourne, VIC, Australia.
Chris Y ChiuImmunology and Diabetes Unit, St. Vincent's Institute of Medical Research, Melbourne, VIC, Australia.
Xin LiuImmunology and Diabetes Unit, St. Vincent's Institute of Medical Research, Melbourne, VIC, Australia.
Eleonora TresoldiImmunology and Diabetes Unit, St. Vincent's Institute of Medical Research, Melbourne, VIC, Australia.
Abby FosterImmunology and Diabetes Unit, St. Vincent's Institute of Medical Research, Melbourne, VIC, Australia.
Laura KingImmunology and Diabetes Unit, St. Vincent's Institute of Medical Research, Melbourne, VIC, Australia.
Fergus J CameronDepartment of Endocrinology and Diabetes, Royal Children's Hospital, Melbourne, VIC, Australia.
Stuart I ManneringImmunology and Diabetes Unit, St. Vincent's Institute of Medical Research, Melbourne, VIC, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antigen-driven T-cell proliferation is often measured using fluorescent dye dilution assays, such as the CFSE-based proliferation assay. Dye dilution assays have been powerful tools to detect human CD4

Indexed as

AutoantigensCD4-Positive T-LymphocytesCell ProliferationDiabetes Mellitus, Type 1Lymphocyte ActivationTetanus ToxoidAdultC-PeptideFemaleHumansMaleYoung AdultAutoantigensC-PeptideTetanus Toxoidantigen specific T cellautoimmunityCD4+ T cellCFSE assayclonal expansionC-peptideproliferationtetanus toxoid

Identifiers

PMID39530093
PMCPMC11550966

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.