Evidence map›Paper›PMID 39530073›Full record

ArticleRevista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia2024

Nipple-sparing mastectomy in young versus elderly patients.

Antônio Luiz Frasson, Isabela Miranda, Betina Vollbrecht, Carolina Malhone, Ana Beatriz Falcone, Fernanda Barbosa, Francisco Pimentel Cavalcante, Martina Lichtenfels

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Antônio Luiz FrassonHospital Israelita Albert Einstein São PauloSP Brazil Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID https://orcid.org/0000-0003-1860-6898
Isabela MirandaUniversidade Católica do Rio Grande do Sul Porto AlegreRS Brazil Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil.ORCID https://orcid.org/0000-0002-9878-8996
Betina VollbrechtUniversidade Católica do Rio Grande do Sul Porto AlegreRS Brazil Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil.ORCID https://orcid.org/0000-0002-7309-6029
Carolina MalhoneHospital Israelita Albert Einstein São PauloSP Brazil Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID https://orcid.org/0000-0002-0713-8315
Ana Beatriz FalconeHospital Israelita Albert Einstein São PauloSP Brazil Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID https://orcid.org/0000-0002-0267-9390
Fernanda BarbosaHospital Israelita Albert Einstein São PauloSP Brazil Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID https://orcid.org/0000-0002-6725-1993
Francisco Pimentel CavalcanteHospital Geral de Fortaleza FortalezaCE Brazil Hospital Geral de Fortaleza, Fortaleza, CE, Brazil.ORCID https://orcid.org/0000-0002-7156-2890
Martina LichtenfelsHospital Israelita Albert Einstein São PauloSP Brazil Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID https://orcid.org/0000-0003-4783-4646

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: In this study, we compared indications and outcomes of 115 young (< 40 years) versus 40 elderly (> 60 years) patients undergoing nipple-sparing mastectomy (NSM) as risk-reducing surgery or for breast cancer (BC) treatment. Methods: Between January 2004 and December 2018, young and elderly patients undergoing NSM with complete data from at least 6 months of follow-up were included. Results: BC treatment was the main indication for NSM, observed in 85(73.9%) young versus 33(82.5%) elderly patients, followed by risk-reducing surgery in 30(26.1%) young versus 7(17.5%) elderly patients. Complication rates did not differ between the age groups. At a median follow-up of 43 months, the overall recurrence rate was higher in the younger cohort (p = 0.04). However, when stratified into local, locoregional, contralateral, and distant metastasis, no statistical difference was observed. During the follow-up, only 2(1.7%) young patients died. Conclusion: Our findings elucidate a higher recurrence rate of breast cancer in younger patients undergoing NSM, which may correlate with the fact that age is an independent prognostic factor. High overall survival and low complication rates were evidenced in the two groups showing the safety of NSM for young and elderly patients.

Indexed as

Breast NeoplasmsNipplesAdultAgedAge FactorsFemaleHumansMastectomy, SubcutaneousMiddle AgedNeoplasm Recurrence, LocalOrgan Sparing TreatmentsRetrospective StudiesTreatment OutcomeAge factorsBreast neoplasmBreast neoplasmsMastectomyNipplessubcutaneousYoung adult

Identifiers

PMID39530073
PMCPMC11554330

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.