Evidence map›Paper›PMID 39529956›Full record

ArticleInnovation (Cambridge (Mass.))2024

Improving risk stratification for 2022 European LeukemiaNet favorable-risk patients with acute myeloid leukemia.

Kellie J Archer, Han Fu, Krzysztof Mrózek, Deedra Nicolet, Alice S Mims, Geoffrey L Uy, Wendy Stock, John C Byrd, Wolfgang Hiddemann, Klaus H Metzeler and 10 more

Abstract read
In one paragraph

Article in Innovation (Cambridge (Mass.)), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Kellie J ArcherDivision of Biostatistics, College of Public Health, The Ohio State University, Columbus, OH, USA.
Han FuGoogle, Inc., Mountain View, CA, USA.
Krzysztof MrózekClara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
Deedra NicoletClara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
Alice S MimsClara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
Geoffrey L UyDepartment of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, MO, USA.
Wendy StockDepartment of Medicine, Section of Hematology/Oncology, University of Chicago, Chicago, IL, USA.
John C ByrdDepartment of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA.
Wolfgang HiddemannDepartment of Medicine III, University Hospital, LMU Munich, Munich, Germany.
Klaus H MetzelerDepartment of Oncology and Hematology, Hospital Barmherzige Brüder, Regensburg, Germany.
Christian RauschDepartment of Medicine III, University Hospital, LMU Munich, Munich, Germany.
Utz KrugDepartment of Medicine 3, Klinikum Leverkusen, Leverkusen, Germany.
Cristina SauerlandInstitute of Biostatistics and Clinical Research, University of Münster, Münster, Germany.
Dennis GörlichInstitute of Biostatistics and Clinical Research, University of Münster, Münster, Germany.
Wolfgang E BerdelDepartment of Medicine A, University Hospital Münster, Münster, Germany.
Bernhard J WoermannGerman Society of Hematology and Oncology, Berlin, Germany.
Jan BraessDepartment of Oncology and Hematology, Hospital Barmherzige Brüder, Regensburg, Germany.
Karsten SpiekermannDepartment of Medicine III, University Hospital, LMU Munich, Munich, Germany.
Tobias HeroldDepartment of Medicine III, University Hospital, LMU Munich, Munich, Germany.
Ann-Kathrin EisfeldClara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.

Funding

Penalized mixture cure models for identifying genomic features associated with outcome in acute myeloid leukemiaR01LM013879 · NLM · OHIO STATE UNIVERSITY · PI ARCHER, KELLIE J. · 2022 to 2025
$1.0M
Clinician Scientist in LeukemiaR50CA275927 · NCI · WASHINGTON UNIVERSITY · PI GEOFFREY L UY · 2023 to 2026
$531k
NCI NIH HHS R50 CA275927NLM NIH HHS R01 LM013879
6 · The paper itself

Abstract

Assignment of patients diagnosed with acute myeloid leukemia (AML) to the 2022 European LeukemiaNet (ELN) favorable genetic risk group has important clinical implications, as allogeneic stem cell transplantation in first complete remission (CR) is not advised due to a relatively good outcome of patients receiving chemotherapy alone and transplant-associated mortality. However, not all favorable genetic risk patients experience long-term relapse-free survival (RFS), making recognition of patients who would most likely be cured of high importance. We analyzed 297 patients aged <60 years with

Identifiers

PMID39529956
PMCPMC11551470

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.