Evidence map›Paper›PMID 39529841›Full record

ArticleBioinformatics advances2024

Phylogenetic-informed graph deep learning to classify dynamic transmission clusters in infectious disease epidemics.

Chaoyue Sun, Yanjun Li, Simone Marini, Alberto Riva, Dapeng Oliver Wu, Ruogu Fang, Marco Salemi, Brittany Rife Magalis

Abstract read
In one paragraph

Article in Bioinformatics advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chaoyue SunNSF Center for Big Learning, University of Florida, Gainesville, FL 32611, United States.ORCID https://orcid.org/0000-0003-0913-5668
Yanjun LiNSF Center for Big Learning, University of Florida, Gainesville, FL 32611, United States.ORCID https://orcid.org/0000-0002-6277-4189
Simone MariniDepartment of Epidemiology, University of Florida, Gainesville, FL 32610, United States.ORCID https://orcid.org/0000-0002-5704-3533
Alberto RivaInterdisciplinary Center for Biotechnology Research, University of Florida, Gainesville, FL 32610, United States.ORCID https://orcid.org/0000-0001-9150-8333
Dapeng Oliver WuNSF Center for Big Learning, University of Florida, Gainesville, FL 32611, United States.
Ruogu FangDepartment of Electrical and Computer Engineering, Herbert Wertheim College of Engineering, University of Florida, Gainesville, FL 32603, United States.
Marco SalemiDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL 32610, United States.ORCID https://orcid.org/0000-0003-0136-2102
Brittany Rife MagalisDepartment of Biochemistry and Molecular Genetics, University of Louisville, Louisville, KY 40202, United States.ORCID https://orcid.org/0000-0001-6088-4651

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Motivation: In the midst of an outbreak, identification of groups of individuals that represent risk for transmission of the pathogen under investigation is critical to public health efforts. Dynamic transmission patterns within these clusters, whether it be the result of changes at the level of the virus (e.g. infectivity) or host (e.g. vaccination), are critical in strategizing public health interventions, particularly when resources are limited. Phylogenetic trees are widely used not only in the detection of transmission clusters, but the topological shape of the branches within can be useful sources of information regarding the dynamics of the represented population. Results: We evaluated the limitation of existing tree shape metrics when dealing with dynamic transmission clusters and propose instead a phylogeny-based deep learning system - Availability and implementation:

Identifiers

PMID39529841
PMCPMC11552518

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.