Evidence map›Paper›PMID 39529524›Full record

ArticleJournal of the National Cancer Institute. Monographs2024

Acceptability of single-dose HPV vaccination schedule among health-care professionals in Kenya: a mixed-methods study.

Grace Umutesi, Bryan J Weiner, Lynda Oluoch, Elizabeth Bukusi, Maricianah Onono, Betty Njoroge, Lucy Mecca, Kenneth Ngure, Nelly R Mugo, Ruanne V Barnabas

Abstract read
In one paragraph

Article in Journal of the National Cancer Institute. Monographs, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Grace UmutesiDepartment of Global Health, University of Washington, Seattle, WA, USA.ORCID 0000-0001-5932-3187
Bryan J WeinerDepartment of Global Health, University of Washington, Seattle, WA, USA.
Lynda OluochCenter for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya.
Elizabeth BukusiDepartment of Global Health, University of Washington, Seattle, WA, USA.
Maricianah OnonoCenter for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya.
Betty NjorogeCenter for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya.
Lucy MeccaSchool of Public Health, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya.
Kenneth NgureDepartment of Global Health, University of Washington, Seattle, WA, USA.
Nelly R MugoDepartment of Global Health, University of Washington, Seattle, WA, USA.ORCID 0000-0002-2347-006X
Ruanne V BarnabasDivision of Infectious Diseases, Massachusetts General Hospital, Boston, MA, USA.

Funding

Gates Foundation INV-010402
6 · The paper itself

Abstract

backgroundThe World Health Organization recommends a single-dose human papillomavirus (HPV) vaccination schedule for girls and boys to accelerate progress toward cervical cancer elimination. We applied the Theoretical Framework of Acceptability (TFA) within the context of HPV vaccination to assess the acceptability of a single-dose schedule among health-care professionals in Kenya.

methodsA REDCap survey was developed using relevant Theoretical Framework of Acceptability domains and validated with health-care professionals. Descriptive analyses and multivariate Poisson regression were conducted to assess factors associated with increased acceptability. Free-text responses were analyzed using a rapid qualitative approach, and findings were presented using a joint display.

resultsAmong 385 responses, 74.2% of health-care professionals were female and 48.6% were nurses. On average, respondents had been in their position for 60 months, and one-third (33.2%) were based at level-4 facilities. The majority (75.84%) thought that giving a single-dose of the HPV vaccine to adolescent girls and young women was either acceptable or very acceptable. Qualitative findings highlighted that lack of information was the underlying reason for health-care professionals who were resistant, and most clinicians thought that a singled-dose schedule was less burdensome to clinicians and patients. Hospital directors had a non-statistically significantly lower acceptability likelihood than nurses (incident rate ratio = 0.93, 95% confidence interval = 0.45 to 1.71) and health-care professionals at urban facilities had a non-statistically significantly lower acceptability likelihood than clinicians in rural facilities (incident rate ratio = 0.97, 95% confidence interval = 0.83 to 1.13).

conclusionAlthough not statistically significant, predictors of increased acceptability provide information to tailor strategies to increase HPV vaccination coverage and accelerate progress toward cervical cancer elimination.

Indexed as

Health PersonnelImmunization SchedulePapillomavirus InfectionsPapillomavirus VaccinesPatient Acceptance of Health CareUterine Cervical NeoplasmsAdolescentAdultAttitude of Health PersonnelFemaleHumansKenyaMaleMiddle AgedSurveys and QuestionnairesVaccinationPapillomavirus Vaccines

Identifiers

PMID39529524
PMCPMC11555271

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.