Evidence map›Paper›PMID 39529327›Full record

ArticleActa neuropsychiatrica2024

Leptin and leptin receptor gene polymorphisms and depression treatment response.

Ida-Maria Tavast, Anssi Solismaa, Leo-Pekka Lyytikäinen, Nina Mononen, Eeva Moilanen, Mari Hämäläinen, Terho Lehtimäki, Olli Kampman

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In one paragraph

Article in Acta neuropsychiatrica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ida-Maria TavastDepartment of Psychiatry, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.ORCID https://orcid.org/0009-0000-5519-8438
Anssi SolismaaDepartment of Psychiatry, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Leo-Pekka LyytikäinenDepartment of Clinical Chemistry, Tampere University Hospital and Fimlab Laboratories and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Nina MononenDepartment of Clinical Chemistry, Tampere University Hospital and Fimlab Laboratories and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Eeva MoilanenThe Immunopharmacology Research Group, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, Tampere, Finland.
Mari HämäläinenThe Immunopharmacology Research Group, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, Tampere, Finland.
Terho LehtimäkiDepartment of Clinical Chemistry, Tampere University Hospital and Fimlab Laboratories and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Olli KampmanDepartment of Psychiatry, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.ORCID https://orcid.org/0000-0001-6891-2266

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAssociations between leptin (

methodsThe data included 242 depressed patients in secondary psychiatric care. Symptoms of depression were assessed with the Montgomery–Åsberg Depression Rating Scale (MADRS). Previously found

resultsTwo proxy SNPs of

conclusionOur findings suggest that

Indexed as

DepressionLeptinReceptors, LeptinAdultAntidepressive AgentsFemaleGenotypeHumansMaleMiddle AgedPolymorphism, Single NucleotidePsychiatric Status Rating ScalesTreatment OutcomeAntidepressive AgentsLEP protein, humanLEPR protein, humanLeptinReceptors, LeptinDepressiongeneticsleptinleptin receptortreatment outcome

Identifiers

PMID39529327
PMCPMC13130323

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.