ArticleMagnetic resonance in medicine2025
Reproducibility of liver ADC measurements using first moment optimized diffusion imaging.
Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Adaptive Complex Signal Average Diffusion-Weighted MR Imaging of the Liver: Utility in Breath-Hold Imaging: A Retrospective Single-Center Study.Tomography (Ann Arbor, Mich.) · 2026Article
- Optimized acquisition for simultaneous intravoxel incoherent motion and RMagnetic resonance in medicine · 2025Article
- Motion and Flow Robust Free-Breathing Diffusion Kurtosis Imaging of the Kidney.NMR in biomedicine · 2025Article
- Reproducibility of liver ADC measurements using first moment optimized diffusion imaging.Magnetic resonance in medicine · 2025Article
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4 authors.
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Abstract
purposeCardiac-induced liver motion can bias liver ADC measurements and compromise reproducibility. The purpose of this work was to enable motion-robust DWI on multiple MR scanners and assess reproducibility of the resulting liver ADC measurements.
methodsFirst moment-optimized diffusion imaging (MODI) was implemented on three MR scanners with various gradient performances and field strengths. MODI-DWI and conventional Stejskal-Tanner monopolar (MONO) DWI were acquired in eight (N = 8) healthy volunteers on each scanner, and DWI repetitions were combined using three different averaging methods. For each combination of scanner, acquisition, and averaging method, ADC measurements from each liver segment were collected. Systematic differences in ADC values between scanners and methods were assessed with linear mixed effects modeling, and reproducibility was quantified via reproducibility coefficients.
resultsMODI reduced left-right liver lobe ADC bias from 0.43 × 10
conclusionThe feasibility of motion-robust liver DWI using MODI was demonstrated on multiple MR scanners. MODI improved interlobar agreement and reproducibility of ADC measurements in a healthy cohort.
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