Evidence map›Paper›PMID 39529197›Full record

ReviewReproductive biology and endocrinology : RB&E2024

MicroRNAs, endometrial receptivity and molecular pathways.

Soheila Salmasi, Mohammad Saeed Heidar, Mahmood Khaksary Mahabady, Bahman Rashidi, Hamed Mirzaei

Abstract readReview
In one paragraph

Review in Reproductive biology and endocrinology : RB&E, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Soheila SalmasiDepartment of Anatomical Sciences & Cognitive Neuroscience, Faculty  of Medicine,  Tehran Medical Sciences, Islamic  Azad University, Tehran, Iran.
Mohammad Saeed HeidarFaculty of life sciences and Biotechnology, Shahid Beheshti University, Tehran, Iran.
Mahmood Khaksary MahabadyAnatomical Sciences Research Center, Institute for Basic Sciences, Kashan University of Medical Sciences, Kashan, Iran.
Bahman RashidiDepartment of Anatomical Sciences & Cognitive Neuroscience, Faculty  of Medicine,  Tehran Medical Sciences, Islamic  Azad University, Tehran, Iran. b_rashidi@med.mui.ac.ir.
Hamed MirzaeiResearch Center for Biochemistry and Nutrition in Metabolic Diseases, Institute for Basic Sciences, Kashan University of Medical Sciences, Kashan, Iran. mirzaei-h@kaums.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) are a type of specific molecules that control the activities of the uterus, such as the process of cellular maturing and evolution. A lot of substances like growth factors, cytokines, and transcription factors play a role in embryo-endometrial interaction. MiRNAs could regulate various these factors by attaching to the 3' UTR of their mRNAs. Moreover, current research show that miRNAs participate in formation of blood vessels in endometrium (miR-206, miR-17-5p, miR-16-5p…), decidualization (miR-154, miR-181, miR-9…), epithelial-mesenchymal transition (miR-30a-3p), immune response (miR-888, miR-376a, miR-300…) embryo attachment (miR-145, miR-27a,451…) and pinopod formation (mir-223-3p, mir-449a, mir-200c). In this study, the focus is on the role of miRNAs in managing the uterus' receptivity to an embryo and its ability to facilitate attachment. More specifically, we are exploring the mechanisms by which miRNAs regulate the presence of specific molecules involved in this crucial physiological process.

Indexed as

Embryo ImplantationEndometriumMicroRNAsAnimalsEpithelial-Mesenchymal TransitionFemaleHumansPregnancySignal TransductionMicroRNAsEmbryo researchEndometriumMicroRNAUterus

Identifiers

PMID39529197
PMCPMC11552404

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.