Evidence map›Paper›PMID 39529142›Full record

ArticleGenome biology2024

IAMSAM: image-based analysis of molecular signatures using the Segment Anything Model.

Dongjoo Lee, Jeongbin Park, Seungho Cook, Seongjin Yoo, Daeseung Lee, Hongyoon Choi

Abstract read
In one paragraph

Article in Genome biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dongjoo Lee *Portrai, Inc, 78-18, Dongsulla-Gil, Jongno-Gu, Seoul, 03136, Republic of Korea.
Jeongbin Park *Portrai, Inc, 78-18, Dongsulla-Gil, Jongno-Gu, Seoul, 03136, Republic of Korea.
Seungho CookPortrai, Inc, 78-18, Dongsulla-Gil, Jongno-Gu, Seoul, 03136, Republic of Korea.
Seongjin YooPortrai, Inc, 78-18, Dongsulla-Gil, Jongno-Gu, Seoul, 03136, Republic of Korea.
Daeseung LeePortrai, Inc, 78-18, Dongsulla-Gil, Jongno-Gu, Seoul, 03136, Republic of Korea.
Hongyoon ChoiPortrai, Inc, 78-18, Dongsulla-Gil, Jongno-Gu, Seoul, 03136, Republic of Korea. chy100@snu.ac.kr.ORCID 0000-0002-8895-2449

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spatial transcriptomics is a cutting-edge technique that combines gene expression with spatial information, allowing researchers to study molecular patterns within tissue architecture. Here, we present IAMSAM, a user-friendly web-based tool for analyzing spatial transcriptomics data focusing on morphological features. IAMSAM accurately segments tissue images using the Segment Anything Model, allowing for the semi-automatic selection of regions of interest based on morphological signatures. Furthermore, IAMSAM provides downstream analysis, such as identifying differentially expressed genes, enrichment analysis, and cell type prediction within the selected regions. With its simple interface, IAMSAM empowers researchers to explore and interpret heterogeneous tissues in a streamlined manner.

Indexed as

SoftwareGene Expression ProfilingHumansImage Processing, Computer-AssistedTranscriptomeDeep learningH&E imageHistologyImage segmentationSpatial transcriptomics

Identifiers

PMID39529142
PMCPMC11552325

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.