ArticleBMC gastroenterology2024
Association of serum albumin-to-creatinine ratio with in-hospital mortality in patients with severe acute pancreatitis: a retrospective study.
Article in BMC gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Article
- Interpretable machine learning model based on non-contrast computed tomography within 24 hours of admission for early prediction of the risk of severe deterioration of acute pancreatitis.Quantitative imaging in medicine and surgery · 2026Article
- Creatinine-Derived Composite Indices for Improved Mortality Prediction in Dogs with Acute Pancreatitis.Animals : an open access journal from MDPI · 2026Article
- Review
- Application of D-LA and APOB/A1 combined with SIRI score in acute pancreatitis and concurrent infectious pancreatic necrosis.American journal of translational research · 2026Article
- Association between the serum albumin-to-creatinine ratio and prognosis and risk of severe disturbance of consciousness in intracerebral hemorrhage patients.Scientific reports · 2025Article
- Association of serum albumin to creatinine ratio with mortality in patients with aortic disease: a cohort study.Scientific reports · 2025Article
- Phospholipase D2: A biomarker implicated in various pancreatic diseases beyond acute pancreatitis.World journal of gastroenterology · 2025Article
- Prognostic value of serum albumin-creatinine ratio as a biomarker in patients treated with immune checkpoint inhibitors.Immunotherapy · 2025Article
- Serum Albumin-Creatinine Ratio and Anthracycline Cardiotoxicity in Patients with Cancer.Journal of clinical medicine · 2025Article
- Effect of octreotide combined with ulinastatin on the creatinine-to-albumin ratio and systemic immune-inflammation index in patients with severe acute pancreatitis.American journal of translational research · 2025Article
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6 authors.
Funding
Abstract
backgroundThe serum albumin-to-serum creatinine ratio (sACR) is independently associated with the prognosis of multiple diseases. However, its relationship with in-hospital mortality of patients with severe acute pancreatitis (SAP) remains unclear.
methodsPatients diagnosed with SAP between April 2016 and December 2023 were collected. These patients were categorized into low and high sACR groups based on an optimal cut-off value calculated using Youden's index. Multivariate logistic regression analysis was utilized to examine the relationship between sACR levels and the in-hospital mortality. Additionally, a limited restricted cubic spline (RCS) method was employed to evaluate the nonlinear relationship between sACR values and the risk of in-hospital mortality. The potential for unmeasured confounders between sACR levels and in-hospital mortality was also explored through the calculation of the E value.
resultsA total of 114 eligible patients were included in this sutdy. The multivariate logistic regression analysis indicated an independent association between sACR levels and in-hospital mortality (p < 0.001). The RCS analysis demonstrated a linear correlation between sACR values and the risk of in-hospital mortality (P for non-linearity > 0.05), where the risk increased as the sACR value decreased.
conclusionsThe research findings suggest that sACR levels are independently associated with in-hospital mortality of patients with SAP, providing a means for early identification of those at high risk of in-hospital mortality. This early identification may facilitate the optimizing and strengthening of treatments, ultimately leading to improved outcomes.
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