Evidence map›Paper›PMID 39528956›Full record

ArticleBMC gastroenterology2024

Endoscopic resection for esophageal granular cell tumors: report of 62 cases.

Chen Gong, Jing Cheng, Qi Jiang, Jue Wang, Keyi Guo, Jinshan Nie, Pinghong Zhou, Jianwei Hu

Abstract read
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Article in BMC gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

8 authors.

Chen Gong *Endoscopy Center, Zhongshan Hospital of Fudan University, Shanghai, 200032, China.
Jing Cheng *Endoscopy Center, Zhongshan Hospital of Fudan University, Shanghai, 200032, China.
Qi Jiang *Endoscopy Center, Zhongshan Hospital (Xiamen), Fudan University, Shanghai, 200032, China.
Jue WangEndoscopy Center, Zhongshan Hospital of Fudan University, Shanghai, 200032, China.
Keyi GuoEndoscopy Center, Zhongshan Hospital of Fudan University, Shanghai, 200032, China.
Jinshan NieDepartment of Gastroenterology, Taicang Affiliated Hospital of Soochow University, The First People's Hospital of Taicang, Taicang, Jiangsu Province, 215400, China.
Pinghong ZhouEndoscopy Center, Zhongshan Hospital of Fudan University, Shanghai, 200032, China. zhou.pinghong@zs-hospital.sh.cn.
Jianwei HuEndoscopy Center, Zhongshan Hospital of Fudan University, Shanghai, 200032, China. hu.jianwei@zs-hospital.sh.cn.

Funding

Gusu Health Talents Training Project GSWS2021058Suzhou " National Tutor" Health Youth Talents Development Program SWJKJ2021-15
6 · The paper itself

Abstract

backgroundTo analyze the clinical manifestations, endoscopic features, pathological features, endoscopic resection, and prognosis of esophageal granular cell tumors (GCTs).

methodsThe present study retrospectively analyzed and followed up the clinical data of 62 patients diagnosed with esophageal GCTs who underwent endoscopic resection at Zhongshan Hospital of Fudan University between July 2007 and March 2022. The clinicopathological features, endoscopic diagnosis, and treatment experience of esophageal GCT patients were summarized.

resultsAmong the 62 patients with esophageal GCT, there were 34 males and 28 females, with an average age of 49.3 ± 11.7 years. Only 11 patients had symptoms, such as epigastric discomfort, regurgitation or dysphagia. One patient had multiple lesions, and the rest had single lesions, totaling 63 lesions. Most lesions (53/63) were located in the median and lower esophagus, the diameters ranged from 3 to 22 mm. The endoscopic morphology of the GCTs was molar, flat, hemispherical, or irregular submucosal protuberance. Endoscopic ultrasound (EUS) was performed in 38 cases, most cases (31/38) were hypoechoic, and 32 cases were appeared as homogeneous lesions. There were no complications during or after the endoscopic operations, and the en bloc resection rate was 100%. The negative rate of microscopic incisional margin was 63.5% (40/63). No patients developed recurrence during the follow-up period. The follow-up duration was 21-197 months (100.5 months for average).

conclusionEsophageal GCT is a rare disease with no obvious symptoms and a good prognosis. Endoscopic resection is a safe and effective method of diagnosis and treatment for esophageal GCTs. A microscopic positive tumor margin may not increase the rate of recurrence.

Indexed as

EndosonographyEsophageal NeoplasmsEsophagoscopyGranular Cell TumorAdultAgedFemaleHumansMaleMiddle AgedNeoplasm Recurrence, LocalPrognosisRetrospective StudiesTreatment OutcomeClinical manifestationEndoscopic featuresEndoscopic resectionEsophageal granular cell tumors

Identifiers

PMID39528956
PMCPMC11552359

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