Evidence map›Paper›PMID 39528897›Full record

ArticleInternational urology and nephrology2025

Sodium-chloride difference is not strongly correlated with base excess in chronic kidney disease: an anion gap problem.

Moritz Kerbl-Knapp, Gregor Lindner, Georg-Christian Funk, Christoph Schwarz

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Article in International urology and nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Moritz Kerbl-KnappDepartment of Internal Medicine 1, Pyhrn-Eisenwurzenklinikum Steyr, Steyr, Austria. Moritz.Kerbl-Knapp@ooeg.at.ORCID http://orcid.org/0009-0006-1114-7106
Gregor LindnerClinical Emergency Medicine, Kepler Universitätsklinikum, Johannes Kepler University, Linz, Austria.
Georg-Christian FunkDepartment of Medicine 2 with Pneumology, Klinik Ottakring, Vienna, Austria.
Christoph SchwarzDepartment of Internal Medicine 1, Pyhrn-Eisenwurzenklinikum Steyr, Steyr, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe prevalence of metabolic acidosis is high in patients with chronic kidney disease (CKD). For the diagnosis, a blood gas analysis is necessary, but not always available. The aim of the study was to evaluate the base excess (BE) of the sodium-chloride difference (BE METHODS AND STATISTICAL ANALYSIS: We retrospectively performed acid-base analyses of 168 non-dialysed patients with CKD according to the physiologic and to the Stewart's approach. We performed linear regression analysis, Bland-Altman plot and receiver operating characteristics (ROC) analysis of BE

resultsThe corrected R

conclusionsThe BE

Indexed as

Acid-Base EquilibriumAcidosisRenal Insufficiency, ChronicSodium ChlorideAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesROC CurveSodium ChlorideAcid–base homeostasisChronic kidney diseaseHyperchloremic metabolic acidosisSodium–chloride difference

Identifiers

PMID39528897

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.