Evidence map›Paper›PMID 39528853›Full record

ReviewProbiotics and antimicrobial proteins2025

Antimicrobial Peptides: Mechanism, Expressions, and Optimization Strategies.

Huabiao Miao, Lu Wang, Qian Wu, Zunxi Huang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Probiotics and antimicrobial proteins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Phospholipid-Coated FeAntibiotics (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Huabiao Miao *School of Life Science, Yunnan Normal University, Kunming, 650500, China.
Lu Wang *School of Life Science, Yunnan Normal University, Kunming, 650500, China.
Qian WuSchool of Life Science, Yunnan Normal University, Kunming, 650500, China.
Zunxi HuangSchool of Life Science, Yunnan Normal University, Kunming, 650500, China. huangzunxi@163.com.

Funding

National Natural Science Foundation of China 32260015
6 · The paper itself

Abstract

Antimicrobial peptides (AMPs) are favoured because of their broad-spectrum antimicrobial properties and because they do not easily develop microbial resistance. However, the low yield and difficult extraction processes of AMPs have become bottlenecks in large-scale industrial applications and scientific research. Microbial recombinant production may be the most economical and effective method of obtaining AMPs in large quantities. In this paper, we review the mechanism, summarize the current status of microbial recombinant production, and focus on strategies to improve the yield and activity of AMPs, in order to provide a reference for their large-scale production.

Indexed as

Antimicrobial PeptidesHumansRecombinant ProteinsAntimicrobial PeptidesRecombinant ProteinsAntimicrobial peptideExpression strategiesFusion proteinGene co-expressionStructural modification

Identifiers

PMID39528853

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.