Evidence map›Paper›PMID 39528496›Full record

ArticleScientific data2024

The Brain Image Library: A Community-Contributed Microscopy Resource for Neuroscientists.

Mariah Kenney, Iaroslavna Vasylieva, Greg Hood, Ivan Cao-Berg, Luke Tuite, Rozita Laghaei, Megan C Smith, Alan M Watson, Alexander J Ropelewski

Abstract readDataset
In one paragraph

Article in Scientific data, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. A FAIR road to a bioAFM databank.Nature methods · 2026
    Article
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  3. Article
  4. A Community Standard Multispecies Cell Atlas of the Basal Ganglia.bioRxiv : the preprint server for biology · 2026
    Article
  5. Article
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  7. Article
  8. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Mariah Kenney *Pittsburgh Supercomputing Center, Carnegie Mellon University, Pittsburgh, PA, 15213, USA.
Iaroslavna Vasylieva *Center for Biologic Imaging, University of Pittsburgh, Pittsburgh, PA, 15213, USA.ORCID 0000-0001-8932-763X
Greg HoodPittsburgh Supercomputing Center, Carnegie Mellon University, Pittsburgh, PA, 15213, USA.ORCID 0000-0001-9871-7154
Ivan Cao-BergPittsburgh Supercomputing Center, Carnegie Mellon University, Pittsburgh, PA, 15213, USA.
Luke TuitePittsburgh Supercomputing Center, Carnegie Mellon University, Pittsburgh, PA, 15213, USA.
Rozita LaghaeiPittsburgh Supercomputing Center, Carnegie Mellon University, Pittsburgh, PA, 15213, USA.
Megan C SmithCenter for Biologic Imaging, University of Pittsburgh, Pittsburgh, PA, 15213, USA.
Alan M WatsonCenter for Biologic Imaging, University of Pittsburgh, Pittsburgh, PA, 15213, USA. alan.watson@pitt.edu.ORCID 0000-0003-0632-8296
Alexander J RopelewskiPittsburgh Supercomputing Center, Carnegie Mellon University, Pittsburgh, PA, 15213, USA. ropelews@psc.edu.ORCID 0000-0001-6874-4477

Funding

A Confocal Fluorescence Microscopy Brain Data ArchiveR24MH114793 · NIMH · CARNEGIE-MELLON UNIVERSITY · PI ALEXANDER J ROPELEWSKI, Alan Michael Watson · 2017 to 2026
$10.1M
Ultra-fast high-resolution imaging of whole mouse brain for the study of drug addictionR21DA052419 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FREYBERG, ZACHARY, LOGAN, RYAN W · 2021 to 2022
$448k
National Science Foundation (NSF) 2137603National Science Foundation (NSF) 2138259National Science Foundation (NSF) 2138286National Science Foundation (NSF) 2138296National Science Foundation (NSF) 2138307National Science Foundation (NSF) ACI-1548562National Science Foundation (NSF) ACI-1928147NIDA NIH HHS R21 DA052419NIMH NIH HHS R24 MH114793U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) R24-MH-114793U.S. Department of Health & Human Services | NIH | National Institute on Drug Abuse (NIDA) R21-DA-052419
6 · The paper itself

Abstract

Advancements in microscopy techniques and computing technologies have enabled researchers to digitally reconstruct brains at micron scale. As a result, community efforts like the BRAIN Initiative Cell Census Network (BICCN) have generated thousands of whole-brain imaging datasets to trace neuronal circuitry and comprehensively map cell types. This data holds valuable information that extends beyond initial analyses, opening avenues for variation studies and robust classification of cell types in specific brain regions. However, the size and heterogeneity of these imaging data have historically made storage, sharing, and analysis difficult for individual investigators and impractical on a broad community scale. Here, we introduce the Brain Image Library (BIL), a public resource serving the neuroscience community that provides a persistent centralized repository for brain microscopy data. BIL currently holds thousands of brain datasets and provides an integrated analysis ecosystem, allowing for exploration, visualization, and data access without the need to download, thus encouraging scientific discovery and data reuse.

Indexed as

BrainMicroscopyNeurosciencesResidence CharacteristicsDatabases, FactualHumans

Identifiers

PMID39528496
PMCPMC11555234

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.