Evidence map›Paper›PMID 39528457›Full record

ArticleNature communications2024

p14

Eric Gibbs, Qi Miao, Mylene Ferrolino, Richa Bajpai, Aila Hassan, Aaron H Phillips, Aaron Pitre, Rainer Kümmerle, Shondra Miller, Gergely Nagy and 5 more

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Tyrosine phosphorylation unfolds nucleophosmin and disrupts its integration into the nucleolus.Proceedings of the National Academy of Sciences of the United States of America · 2026
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4 · The record

Corrections and comments

  • Update of
    p142023
5 · Who and what money

Authors and funding

15 authors.

Eric GibbsDepartment of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Qi MiaoDepartment of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Mylene FerrolinoDepartment of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.ORCID 0000-0002-9693-8401
Richa BajpaiCenter for Advanced Genome Engineering, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Aila HassanBruker Switzerland AG, Fällanden, Switzerland.
Aaron H PhillipsDepartment of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Aaron PitreCell and Tissue Imaging Shared Resource, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.ORCID 0000-0002-3017-2140
Rainer KümmerleBruker Switzerland AG, Fällanden, Switzerland.
Shondra MillerCenter for Advanced Genome Engineering, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.ORCID 0000-0002-3793-585X
Gergely NagyNeutron Scattering Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA.ORCID 0000-0003-2742-0198
Wellington LeiteNeutron Scattering Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA.
William HellerNeutron Scattering Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA.ORCID 0000-0001-6456-2975
Chris StanleyComputational Sciences and Engineering Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA.ORCID 0000-0002-4226-7710
Barbara PerroneBruker Switzerland AG, Fällanden, Switzerland.
Richard KriwackiDepartment of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA. Richard.Kriwacki@stjude.org.ORCID 0000-0002-9798-6018

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Heather M Brandt · 1985 to 2026
$166.9M
Understanding Phase Separation in Biology and DiseaseR35GM131891 · NIGMS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI RICHARD W KRIWACKI · 2019 to 2026
$3.3M
Regulation of ARF tumor suppressor function by biological phase separationF32GM133078 · NIGMS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI GIBBS, ERIC B · 2020 to 2020
$67k
NCI NIH HHS P30 CA021765NIGMS NIH HHS F32 GM133078NIGMS NIH HHS R35 GM131891U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) 5R35GM131891
6 · The paper itself

Abstract

NPM1 is an abundant nucleolar chaperone that, in addition to facilitating ribosome biogenesis, contributes to nucleolar stress responses and tumor suppression through its regulation of the p14 Alternative Reading Frame tumor suppressor protein (p14

Indexed as

Cell NucleolusNuclear ProteinsNucleophosminTumor Suppressor Protein p14ARFCell ProliferationHumansHydrophobic and Hydrophilic InteractionsPhase SeparationProtein BindingTumor Suppressor Protein p53NPM1 protein, humanNuclear ProteinsNucleophosminTumor Suppressor Protein p14ARFTumor Suppressor Protein p53

Identifiers

PMID39528457
PMCPMC11555371

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.