Evidence map›Paper›PMID 39528387›Full record

ArticleChemical research in toxicology2024

Melatonin Vapes Contain Potential Contaminants and Alter the Human Bronchial Epithelial Transcriptome.

Kevin D Schichlein, Hye-Young H Kim, Charlotte A Love, Tara N Guhr Lee, Charles R Esther, Ned A Porter, Meghan E Rebuli, Brandie M Ehrmann, Phillip W Clapp, Ilona Jaspers

Abstract read
In one paragraph

Article in Chemical research in toxicology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kevin D SchichleinCurriculum in Toxicology & Environmental Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Hye-Young H KimDepartment of Chemistry and Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37235, United States.
Charlotte A LoveCurriculum in Toxicology & Environmental Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.ORCID 0000-0002-5775-989X
Tara N Guhr LeeDepartment of Chemistry and Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37235, United States.
Charles R EstherDepartment of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Ned A PorterDepartment of Chemistry and Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37235, United States.ORCID 0000-0002-4447-7690
Meghan E RebuliCurriculum in Toxicology & Environmental Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.ORCID 0000-0003-1918-2257
Brandie M EhrmannDepartment of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Phillip W ClappDepartment of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Ilona JaspersCurriculum in Toxicology & Environmental Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.ORCID 0000-0001-8728-0305

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Melissa A. Troester · 2001 to 2026
$36.3M
TOXICOLOGYT32ES007126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ILONA JASPERS, Bernard E. Weissman · 1985 to 2026
$13.0M
Health effects of cannabidiol vaping productsR01HL171967 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ILONA JASPERS · 2024 to 2026
$2.0M
NHLBI NIH HHS R01 HL171967NIEHS NIH HHS P30 ES010126NIEHS NIH HHS T32 ES007126
6 · The paper itself

Abstract

Melatonin vaping products, touted for their faster absorption than oral melatonin supplements, have been gaining popularity among adolescents as sleep aid. Here, we elucidated the response of human bronchial epithelial cells (hBECs) to high levels of melatonin from vaped aerosols, investigated the uptake of melatonin by hBECs

Indexed as

BronchiEpithelial CellsMelatoninTranscriptomeCells, CulturedHumansMelatonin

Identifiers

PMID39528387
PMCPMC12273598

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.