Evidence map›Paper›PMID 39527667›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Acoustofluidic Tweezers Integrated with Droplet Sensing Enable Multifunctional Closed-Loop Droplet Manipulation.

Mingyang Sui, Huijuan Dong, Guanyu Mu, Zhen Yang, Ye Ai, Jie Zhao

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Spin-Orbit Angular Momentum Conversion in Coupled Nonparaxial Bessel Acoustic Vortices.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  4. Article
  5. Sound-controlled fluidic processor.Science advances · 2025
    Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mingyang SuiState Key Laboratory of Robotics and System, Harbin Institute of Technology, Harbin, 150001, China.
Huijuan DongState Key Laboratory of Robotics and System, Harbin Institute of Technology, Harbin, 150001, China.
Guanyu MuState Key Laboratory of Robotics and System, Harbin Institute of Technology, Harbin, 150001, China.
Zhen YangInstitute of Orthopedics, Chinese PLA General Hospital, Beijing Key Laboratory of Regenerative Medicine in Orthopedics, Key Laboratory of Musculoskeletal Trauma & War Injuries PLA, Beijing, 100853, China.
Ye AiPillar of Engineering Product Development, Singapore University of Technology and Design, Singapore, 487372, Singapore.ORCID 0000-0001-8638-1649
Jie ZhaoState Key Laboratory of Robotics and System, Harbin Institute of Technology, Harbin, 150001, China.

Funding

China Scholarship Council 202306120147Ministry of Education, Singapore MOE-T2EP50221-0012National Natural Science Foundation of China 52275014National Natural Science Foundation of China U23A20617
6 · The paper itself

Abstract

Droplet manipulation technologies with surface acoustic waves attract significant attention for applications in fluid handling and bioanalysis. However, existing technologies face challenges in automation, precision, and functional integration, limiting broader applications. In this work, a highly integrated droplet-sensing acoustofluidic tweezer is developed, incorporating orthogonally arranged slanted finger interdigital transducers and a custom-designed control and detection circuit system. Using a single acoustic device, this tweezer enables switchable acoustic droplet manipulation and detection, providing multifunctional closed-loop manipulation of on-chip microliter-scale droplets. The platform takes advantage of the wideband frequency response characteristics of the transducers, along with an automated droplet detection algorithm, enabling high-precision detection of central positions, edge positions, contact diameters, and the number of droplets. With this feedback, automated closed-loop control of various droplet manipulation functions, including transportation, merging, mixing, splitting, and internal particle enrichment, is achieved for the first time on a single acoustic platform. This significantly enhances the precision, efficiency, and fault tolerance of the manipulation process. This droplet-sensing acoustofluidic tweezer provides an innovative acoustic solution for droplet manipulation technologies in fields such as fluid processing and biosensing, demonstrating significant application potential.

Indexed as

AcousticsEquipment DesignMicrofluidic Analytical TechniquesTransducersacoustic detectionclosed‐loop systemdroplet manipulationslanted finger interdigital transducerssurface acoustic waves

Identifiers

PMID39527667
PMCPMC11714172

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.