Evidence map›Paper›PMID 39527246›Full record

ArticleCellular and molecular life sciences : CMLS2024

The phospholamban R14del generates pathogenic aggregates by impairing autophagosome-lysosome fusion.

Elizabeth Vafiadaki, Evangelia G Kranias, Aristides G Eliopoulos, Despina Sanoudou

Abstract read
In one paragraph

Article in Cellular and molecular life sciences : CMLS, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Genetic landscape of phospholamban cardiomyopathies.Frontiers in cell and developmental biology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elizabeth VafiadakiCenter of Basic Research, Biomedical Research Foundation of the Academy of Athens, Athens, 11527, Greece. lvafiadaki@bioacademy.gr.
Evangelia G KraniasCenter of Basic Research, Biomedical Research Foundation of the Academy of Athens, Athens, 11527, Greece.
Aristides G EliopoulosCenter of Basic Research, Biomedical Research Foundation of the Academy of Athens, Athens, 11527, Greece.
Despina SanoudouCenter of Basic Research, Biomedical Research Foundation of the Academy of Athens, Athens, 11527, Greece. dsanoudou@med.uoa.gr.ORCID http://orcid.org/0000-0003-3704-1941

Funding

Fondation Leducq CURE-PLaN, 18CVD01
6 · The paper itself

Abstract

Phospholamban (PLN) plays a crucial role in regulating sarcoplasmic reticulum (SR) Ca

Indexed as

AutophagosomesAutophagyCalciumCalcium-Binding ProteinsLysosomesAnimalsCardiomyopathiesHumansMembrane FusionMutationMyocytes, CardiacPhospholambanCalciumCalcium-Binding ProteinsPhospholambanAggregatesAutophagyCardiomyopathyPrecision medicine

Identifiers

PMID39527246
PMCPMC11554986

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.