ArticlePsychopharmacology2025
Behavioral studies of the abuse potential and anesthetic and sedative effects of etomidate in male rodents.
Article in Psychopharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Development of a Quantum Dot-Based Immunochromatographic Assay for Rapid and Sensitive Detection of Non-Medical Etomidate Abuse.Biosensors · 2026Article
- Pharmacological effect of (±)-trans-3-methylfentanyl and (±)-cis-3-methylfentanyl.Psychopharmacology · 2026Article
- Beyond adrenal suppression: a comprehensive post-marketing safety profile of etomidate from real world data.Frontiers in medicine · 2026Article
- Identification of two novel imidazole-derived GABA agonists butomidate and tf-etomidate in e-cigarette liquids.Forensic toxicology · 2026Article
- Assessment of abuse potential of furanylfentanyl and tetrahydrofuranylfentanyl.Psychopharmacology · 2025Article
- Rapid quantification and validation of etomidate and dexmedetomidine blood concentrations in rats using a novel portable mass spectrometer.Frontiers in veterinary science · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
rationaleEtomidate is a short-acting general anesthetic for clinical use and has been used as alternative to propofol or added to the powdered drug and e-cigarette cartridges recently, leading to an increase in abuse. But there have been no studies conducted on the abuse potential of etomidate. OBJECTIVES AND
methodsThis study aimed to evaluate the abuse potential of etomidate via conditioned place preference (CPP) and self-administration tests, reflecting its rewarding and reinforcing effects. In addition, righting reflex and open-field tests were conducted to evaluate the anesthetic and sedative effects of etomidate.
resultsIn male mice, the ED
conclusionsThese results clearly demonstrate that etomidate has rewarding and reinforcing effects in male rodents, as well as effects on anesthesia and motor inhibition. These findings indicate the possibility of abuse potential in humans using etomidate.
Indexed as
Identifiers
39527141What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.