Evidence map›Paper›PMID 39526434›Full record

ArticleThe Gerontologist2025

The Intersecting Effects of Lifetime Experiences of Homelessness and Incarceration on Cognitive Aging and Dementia Risk Factors in the United States.

Douglas William Hanes, Sean A P Clouston

Abstract read
In one paragraph

Article in The Gerontologist, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Douglas William HanesProgram in Public Health, Renaissance School of Medicine, Stony Brook University, Stony Brook, New York, USA.ORCID 0000-0003-2186-5540
Sean A P CloustonProgram in Public Health, Renaissance School of Medicine, Stony Brook University, Stony Brook, New York, USA.ORCID 0000-0002-6124-0329

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Social inequalities and the onset of Alzheimer's pathology: The role of Race/Ethnicity, cognitive reserve, and occupational complexityRF1AG058595 · NIA · STATE UNIVERSITY NEW YORK STONY BROOK · PI CLOUSTON, SEAN · 2019 to 2019
$3.3M
Alzheimer's Association Research Fellowship AARFD-231151386NIA NIH HHS NIA U01AG009740NIA NIH HHS RF1 AG058595NIA NIH HHS U01 AG009740NIH HHS
6 · The paper itself

Abstract

BACKGROUND AND

objectivesAlzheimer's disease and related dementias (ADRD) remain a pressing concern in the United States, which also has one of the highest incarceration rates worldwide. Existing research has analyzed dementia risk and care among currently incarcerated and homeless populations; this paper fills a gap by examining later-life cognitive disparities facing formerly incarcerated and/or homeless individuals. RESEARCH DESIGN AND

methodsUsing Health and Retirement Study data (1998-2018), we tested whether formerly homeless and/or incarcerated people had earlier onset of cognitive decline, and whether they were more likely to have modifiable risk factors for ADRD than those without such experiences. We estimated prevalence of mild cognitive impairment (MCI), dementia, and self-reported ADRD diagnosis. We also used repeated observations of cognitive functioning coupled with nested nonlinear regression to examine the onset of accelerated cognitive decline.

resultsAdjusting for demographic variables, formerly homeless and/or incarcerated participants have increased odds of having risk factors for dementia, including smoking, drinking alcohol, depression, mental illness, and discrimination from healthcare providers and police. Diagnosis of MCI and ADRD were more common among participants reporting a history of incarceration or homelessness. Nested nonlinear regression revealed that previous experiences of incarceration or homelessness-alone or together-are associated with earlier onset of accelerated cognitive decline compared with those who experienced neither. DISCUSSION AND IMPLICATIONS: This study suggests that, even if they occur earlier in life, homelessness and incarceration experiences may increase risk of poorer cognitive health in late life. Future work is warranted to understand the lifelong consequences linked to this adversity.

Indexed as

Alzheimer DiseaseCognitive AgingCognitive DysfunctionDementiaIll-Housed PersonsPrisonersAgedAged, 80 and overFemaleHumansIncarcerationMaleMiddle AgedPrevalenceRisk FactorsUnited StatesCriminalizationDiscriminationMild cognitive impairmentPrisonUnhoused

Identifiers

PMID39526434
PMCPMC12082290

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.