Evidence map›Paper›PMID 39526356›Full record

ArticleJournal of the American Heart Association2024

Association of Systemic Inflammatory Response Syndrome With Cardiovascular Events After Mitral Transcatheter Edge-to-Edge Repair.

Carlo Mannina, Akarsh Sharma, Andreina Carbone, Eduardo Bossone, Antonino Tuttolomondo, Edgar Argulian, Eric Neibart, Michael B Hadley, Jonathan Halperin, George Dangas and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Carlo ManninaDepartment of Medicine Icahn School of Medicine at Mount Sinai New York NY.ORCID 0000-0003-1324-1869
Akarsh SharmaDepartment of Medicine Icahn School of Medicine at Mount Sinai New York NY.ORCID 0000-0001-9654-7155
Andreina CarboneUnit of Cardiology University Hospital "Luigi Vanvitelli" Naples Italy.ORCID 0000-0002-2190-7010
Eduardo BossoneDepartment of Public Health Federico II University Naples Italy.ORCID 0000-0003-2769-9950
Antonino TuttolomondoDepartment of Internal Medicine University of Palermo Palermo Italy.ORCID 0000-0001-6440-7318
Edgar ArgulianDivision of Cardiology, Mount Sinai Morningside Icahn School of Medicine at Mount Sinai New York NY.ORCID 0000-0003-2106-2668
Eric NeibartThe Zena and Michael A. Wiener Cardiovascular Institute, The Mount Sinai Fuster Hospital Icahn School of Medicine at Mount Sinai New York NY.
Michael B HadleyThe Zena and Michael A. Wiener Cardiovascular Institute, The Mount Sinai Fuster Hospital Icahn School of Medicine at Mount Sinai New York NY.ORCID 0000-0002-3794-7877
Jonathan HalperinThe Zena and Michael A. Wiener Cardiovascular Institute, The Mount Sinai Fuster Hospital Icahn School of Medicine at Mount Sinai New York NY.ORCID 0000-0002-8318-5471
George DangasThe Zena and Michael A. Wiener Cardiovascular Institute, The Mount Sinai Fuster Hospital Icahn School of Medicine at Mount Sinai New York NY.ORCID 0000-0001-7502-8049
Samin K SharmaThe Zena and Michael A. Wiener Cardiovascular Institute, The Mount Sinai Fuster Hospital Icahn School of Medicine at Mount Sinai New York NY.ORCID 0000-0002-1888-0793
Annapoorna KiniThe Zena and Michael A. Wiener Cardiovascular Institute, The Mount Sinai Fuster Hospital Icahn School of Medicine at Mount Sinai New York NY.ORCID 0000-0002-7189-3307
Stamatios LerakisThe Zena and Michael A. Wiener Cardiovascular Institute, The Mount Sinai Fuster Hospital Icahn School of Medicine at Mount Sinai New York NY.ORCID 0000-0001-7487-1990

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSystemic inflammatory response syndrome (SIRS) following cardiovascular interventions is associated with adverse events during hospitalization and follow-up. Mitral transcatheter edge-to-edge repair is increasingly utilized for treatment of mitral regurgitation (MR). We investigated whether SIRS following mitral transcatheter edge-to-edge repair may occur and be associated with adverse clinical outcomes. METHODS AND

resultsA total of 158 consecutive patients with severe MR undergoing mitral transcatheter edge-to-edge repair were studied. SIRS was defined by leukocytosis (≥12 × 10

conclusionsSIRS after mitral transcatheter edge-to-edge repair is a strong independent predictor of major cardiovascular events. Closer follow-up is warranted because patients with SIRS have more severe MR at follow-up.

Indexed as

Cardiac CatheterizationMitral Valve InsufficiencySystemic Inflammatory Response SyndromeAgedAged, 80 and overFemaleHeart Valve Prosthesis ImplantationHumansLeukocytosisMaleMitral ValveMyocardial InfarctionNeutrophilsRecurrenceRetrospective StudiesRisk Factorsleft ventricular remodelingmajor adverse cardiovascular eventsmitralclipmitral regurgitationmitral transcatheter edge‐to‐edge repairsystemic inflammatory response syndrome

Identifiers

PMID39526356
PMCPMC11681385

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.