ReviewConsortium psychiatricum2024
Biological Methods for Diagnosing Depressive Symptoms in Patients with Schizophrenia: A Narrative Review.
Review in Consortium psychiatricum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
Funding
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Abstract
backgroundDepressive symptoms in patients with schizophrenia lead to more frequent exacerbations of the underlying disease, worsen the prognosis, and increase the risk of suicide. Clinical practitioners continue to face challenges in diagnosing this disorder.
aimThis study aims to analyze published material on biological markers of depressive symptoms in patients with schizophrenia.
methodsThe search of literature was conducted using the following electronic search engines (the total number of relevant papers found is also specified): ACCESSSS (
resultsBased on the available scaterred data, it appears that plasma biomarkers (e.g. C-reactive protein, metabolic parameters, hormones, enzymes, neurotrophic factors) are limited in specificity when it comes to diagnosing depressive symptoms in schizophrenia. Our analysis of the neuroimaging findings showed that depressive manifestations are associated with a decrease in the volume of the gray matter in the parietal, frontal, and temporal lobes (particularly in Broca's and Wernicke's areas) and in specific regions of the prefrontal cortex (including the medial right superior frontal, medial orbitofrontal, and superior and middle frontal gyri). It has been suggested that the
conclusionUnderstanding and identifying depressive symptoms in schizophrenia will improve the quality of care for patients with this disorder.
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