Evidence map›Paper›PMID 39525858›Full record

ArticleMedical hypotheses2024

How the Somatosensory System Adapts to the Motor Change in Stroke: A Hemispheric Shift?

Jordan N Williamson, Beni Mulyana, Rita Huan-Ting Peng, Sanjiv Jain, Wael Hassaneen, Amrendra Miranpuri, Yuan Yang

Abstract read
In one paragraph

Article in Medical hypotheses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Corticomuscular Connectivity and Brain Reorganization Post-Stroke.International IEEE/EMBS Conference on Neural Engineering : [proceedings]. International IEEE EMBS Conference on Neural Engineering · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jordan N WilliamsonUniversity of Illinois Urbana-Champaign, Grainger College of Engineering, Department of Bioengineering, Urbana, IL, USA.
Beni MulyanaUniversity of Illinois Urbana-Champaign, Grainger College of Engineering, Department of Bioengineering, Urbana, IL, USA.
Rita Huan-Ting PengUniversity of Illinois Urbana-Champaign, Grainger College of Engineering, Department of Bioengineering, Urbana, IL, USA.
Sanjiv JainCarle Foundation Hospital, Dr. Elizabeth Hosick Rehabilitation Center, Urbana, IL, USA.
Wael HassaneenCarle Illinois College of Medicine, Urbana, IL, USA.
Amrendra MiranpuriCarle Illinois College of Medicine, Urbana, IL, USA.
Yuan YangUniversity of Illinois Urbana-Champaign, Grainger College of Engineering, Department of Bioengineering, Urbana, IL, USA.

Funding

Shift from Unilateral to Bilateral Sensory-Motor Connectivity in Chronic Hemiparetic StrokeR01HD109157 · NICHD · UNIVERSITY OF OKLAHOMA · PI Yuan Yang · 2022 to 2026
$1.7M
NICHD NIH HHS R01 HD109157
6 · The paper itself

Abstract

Previous studies found that post-stroke motor impairments are associated with damage to the lesioned corticospinal tract and a maladaptive increase in indirect contralesional motor pathways. How the somatosensory system adapts to the change in the use of motor pathways and the role of adaptive sensory feedback to the abnormal movement control of the paretic arm remains largely unknown. We hypothesize that following a unilateral stroke, there is an adaptive hemispheric shift of somatosensory processing toward the contralesional sensorimotor areas to provide sensory feedback support to the contralesional indirect motor pathways. This research could provide new insights related to somatosensory reorganization after stroke, which could enrich future hypothesis-driven therapeutic rehabilitation strategies from a sensory or sensory-motor perspective. Understanding how somatosensory information shifts may provide a target for a novel method to therapeutically prevent and mitigate the emergence and expression of upper limb motor impairments, following a stroke.

Indexed as

Cortical ReorganizationSensorimotor systemStroke

Identifiers

PMID39525858
PMCPMC11542668

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.