Evidence map›Paper›PMID 39525855›Full record

ArticleFrontiers in endocrinology2024

Relationship of thyroid parameters with chronic inflammation in patients with euthyroid type 2 diabetes.

Wei Shi, Dan Chen, Wei Chen, Yulu Chen, Xiaoling Fu, Yong Xiao, Wei Duan, Jing Zhang

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wei ShiDepartment of Endocrinology, Hubei Integrated Traditional Chinese and Western Medicine Hospital, Hubei University of Chinese Medicine, Wuhan, China.
Dan ChenDepartment of Endocrinology, Hubei Integrated Traditional Chinese and Western Medicine Hospital, Hubei University of Chinese Medicine, Wuhan, China.
Wei ChenDepartment of Endocrinology, Hubei Integrated Traditional Chinese and Western Medicine Hospital, Hubei University of Chinese Medicine, Wuhan, China.
Yulu ChenDepartment of Endocrinology, Hubei Integrated Traditional Chinese and Western Medicine Hospital, Hubei University of Chinese Medicine, Wuhan, China.
Xiaoling FuDepartment of Endocrinology, Hubei Integrated Traditional Chinese and Western Medicine Hospital, Hubei University of Chinese Medicine, Wuhan, China.
Yong XiaoDepartment of Endocrinology, Hubei Integrated Traditional Chinese and Western Medicine Hospital, Hubei University of Chinese Medicine, Wuhan, China.
Wei DuanDepartment of Endocrinology, Hubei Integrated Traditional Chinese and Western Medicine Hospital, Hubei University of Chinese Medicine, Wuhan, China.
Jing ZhangDepartment of Endocrinology, Hubei Integrated Traditional Chinese and Western Medicine Hospital, Hubei University of Chinese Medicine, Wuhan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: We evaluated the association of multiple thyroid parameters with the levels interleukin 6 (IL6) and interleukin 8 (IL8) in patients with euthyroid type 2 diabetes (T2D). Methods: A total of 166 adults with euthyroid T2D were examined. Serum IL6, IL8, triiodothyronine (FT3), free thyroxin (FT4), thyroid-stimulating hormone (TSH), five thyroid sensitivity indexes (FT3/FT4, TSH index [TSHI], thyrotroph T4 resistance index [TT4RI], thyroid feedback quantile-based index by FT3 [TFQI Results: The median age was 64 years (IQR: 54.75,70) and the median duration of diabetes was 10 years (IQR: 3,18). Patients with high levels of IL6 (≥2.38 pg/mL) had lower levels of FT3 and TFQI Conclusion: Patients with euthyroid T2D who had lower levels of FT3 had significantly higher levels of IL6, and those with lower levels of TSH and TT4RI had significantly higher levels of IL8.

Indexed as

Diabetes Mellitus, Type 2InflammationInterleukin-6Interleukin-8Thyroid Function TestsThyroid GlandThyrotropinTriiodothyronineAgedBiomarkersChronic DiseaseFemaleHumansMaleMiddle AgedThyroid HormonesBiomarkersCXCL8 protein, humanIL6 protein, humanInterleukin-6Interleukin-8Thyroid HormonesThyrotropinThyroxineTriiodothyroninediabeteseuthyroidinflammationthyroid hormonethyroid hormone sensitivity

Identifiers

PMID39525855
PMCPMC11543494

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.