Evidence map›Paper›PMID 39525805›Full record

ArticleClinical case reports2024

A case of bone resorption in the mentum caused by hyaluronic acid filler in a patient with skeletal Class II jaw deformity.

Takayuki Nakagawa, Shigehiro Ono, Miyuki Sakuma, Yoko Ishida, Kuniko Mizuta, Ryo Uetsuki, Keijyuro Odan, Yuko Shintaku, Masataka Higuchi, Yutaka Matsushita and 4 more

Abstract read
In one paragraph

Article in Clinical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Takayuki NakagawaDepartment of Oral and Maxillofacial Surgery, Program of Dentistry, Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan.ORCID https://orcid.org/0000-0002-3508-0712
Shigehiro OnoDepartment of Oral and Maxillofacial Surgery, Program of Dentistry, Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan.
Miyuki SakumaDepartment of Oral and Maxillofacial Surgery, Program of Dentistry, Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan.
Yoko IshidaDepartment of Oral and Maxillofacial Surgery, Program of Dentistry, Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan.
Kuniko MizutaDepartment of Oral and Maxillofacial Surgery, Program of Dentistry, Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan.
Ryo UetsukiDepartment of Oral and Maxillofacial Surgery, Program of Dentistry, Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan.
Keijyuro OdanDepartment of Oral and Maxillofacial Surgery, Program of Dentistry, Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan.
Yuko ShintakuDepartment of Oral and Maxillofacial Surgery Suita Tokusyukai Hospital Osaka Japan.
Masataka HiguchiDepartment of Oral and Maxillofacial Surgery Suita Tokusyukai Hospital Osaka Japan.
Yutaka MatsushitaDepartment of Oral and Maxillofacial Surgery Suita Tokusyukai Hospital Osaka Japan.
Shunichi KojimaKojima orthodontics dental clinic Osaka Japan.
Isao HirataDepartment of Biomaterials, Program of Dentistry, Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan.
Koichi KatoDepartment of Biomaterials, Program of Dentistry, Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan.
Tomonao AikawaDepartment of Oral and Maxillofacial Surgery, Program of Dentistry, Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Key Clinical Message: Chin augmentation by hyaluronic acid filler injection rarely causes abnormal bone resorption in the mentum. Thus, when taking the history of a patient with jaw deformity, it is imperative to check the history of treatment of the mentum. Abstract: Hyaluronic acid (HA) filler injection is a common procedure in nonsurgical cosmetic chin augmentation. Due to its high biocompatibility and simple injection technique, HA filler injection is a popular procedure. However, adverse events such as allergic reactions and foreign body reactions have been reported in some cases. In this study, we report a case of skeletal Class II jaw deformity in which bone resorption was observed in the mentum after HA filler injection. The purpose of this study is to discuss the indications for HA filler injection in skeletal Class II cases that require orthognathic surgery. The patient was a 30-year-old woman. To improve retrusion of the mentum, she has been receiving HA filler injections in the mentum three times every 6 months in the cosmetic surgery clinic since 2015. However, the retrusion of the mentum did not improve, which prompted here to visit the orthodontic clinic. Radiographs and CT revealed bowl-shaped bone resorption surrounding the foreign bodies in the mentum. She was diagnosed with maxillary protrusion, vertical maxillary excess, mandibular retrusion, and bilateral condylar resorption. Bimaxillary orthognathic surgery (BOGS) and removal of residual HA fillers were planned after completion of the preoperative orthodontic treatment. After BOGS, the foreign bodies were completely removed, and the resorption cavities were filled with excess bone segments from the surgical sites. X-ray photoelectron spectroscopy analysis of the foreign bodies suggested the presence of HA. One year after the BOGS, no progression of condylar resorption occurred, and bone healing at the mentum had a good prognosis. Therefore, the patient underwent reduction and advancement genioplasty. She was satisfied with her facial profile and occlusal function. Unexpected bone resorption in the mentum caused by HA filler injection is often discovered incidentally. Although, patients may feel hesitant to confess their history of treatment of the mentum, it is important to ensure that they are carefully interviewed.

Indexed as

bone resorptionchin augmentationhyaluronic acid (HA)orthognathic surgery

Identifiers

PMID39525805
PMCPMC11543548

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.