Evidence map›Paper›PMID 39525770›Full record

ArticleAnnals of medicine and surgery (2012)2024

Unilateral adrenal metastases as an unusual primary presentation of hepatocellular carcinoma: a case report and literature review.

Raza Gulzar Ghouri, Muhammad Sharjeel, Hamza Naeem, Sikander Abdullah, Umar Abdul Rehman Khalid, Abdul Mabood Basil

Abstract readCase Reports
In one paragraph

Article in Annals of medicine and surgery (2012), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Raza Gulzar GhouriPakistan Kidney and Liver Institute and Research Center.
Muhammad SharjeelPakistan Kidney and Liver Institute and Research Center.
Hamza NaeemKing Edward Medical University, Lahore, Pakistan.
Sikander AbdullahPakistan Kidney and Liver Institute and Research Center.
Umar Abdul Rehman KhalidKing Edward Medical University, Lahore, Pakistan.
Abdul Mabood BasilSpinghar Medical University, Kabul, Afghanistan.ORCID https://orcid.org/0009-0008-2745-1932

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction and importance: Adrenal metastases can rarely present as a solitary clinical manifestation among cases with underlying hepatocellular carcinoma (HCC). Case presentation: The authors present the case of a 53-year-old male with chronic liver disease due to chronic hepatitis C who presented with left flank pain. Imaging revealed a left-sided suprarenal mass. Following multidisciplinary assessment, the patient underwent left-sided nephrectomy and adrenalectomy, whereas histopathological correlation revealed microscopic foci of metastatic HCC in the resected gland. Postoperative abdominal imaging then revealed multifocal dysplastic lesions scattered through both the hepatic lobes. Subsequently, systemic treatment was initiated with sorafenib. Clinical discussion: These types of adrenal metastasis from the liver are extremely uncommon and need detailed evaluation of the liver and other potential metastatic sites. The choice of treatment will be indicated according to the type and site of the tumor. Conclusion: This case highlights the significance of thorough evaluation and individualized management in HCC-associated adrenal metastasis.

Indexed as

adrenalectomyadrenal glandhepatocellular cancermetastasismultidisciplinary approach

Identifiers

PMID39525770
PMCPMC11543188

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.