Evidence map›Paper›PMID 39525713›Full record

ReviewAnnals of medicine and surgery (2012)2024

Foix-Alajouanine syndrome: a comprehensive overview of rare but relevant diagnosis.

Oday Atallah, Yasser F Almealawy, Roua Arian, Assma Dwebi, Amr Badary, Abbas F Abdul Hussein, Vivek Sanker, Saber Zafarshamspour, Bipin Chaurasia, Amit Agrawal and 2 more

Abstract readReview
In one paragraph

Review in Annals of medicine and surgery (2012), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Oday AtallahDepartemnt of Neurosurgery, Hannover Medical School, Hannover, Germany.
Yasser F AlmealawyFaculty of Medicine, University of Kufa, Kufa, Iraq.
Roua ArianFaculty of Medicine, University of Aleppo, Aleppo, Syria.
Assma DwebiFaculty of Medicine, Ludwig-Maximilians-Universität München, Munich.
Amr BadaryDepartemnt of Neurosurgery, Klinikum Dessau, Dessau-Roßlau, Germany.
Abbas F Abdul HusseinFaculty of Medicine, Babylon University, Hilla, Iraq.
Vivek SankerDepartment of Neurosurgery, Trivandrum Medical College, Kerala, India.
Saber ZafarshamspourDepartment of Surgery, Rafsanjan University of Medical Sciences, Rafsanjan, Kerman, Iran.
Bipin ChaurasiaDepartment of Neurosurgery, Neurosurgery Clinic, Birgunj, Nepal.ORCID https://orcid.org/0000-0002-8392-2072
Amit AgrawalDepartment of Neurosurgery, All India Institute of Medical Sciences, Saket Nagar, Bhopal, Madhya Pradesh, India.
Santiago Pastrana BrandesHarvard T.H. Chan School of Public Health, Executive and Continuing Professional Education (ECPE), Boston, Massachusetts, USA.
Mohammed A AzabDepartemnt of Neurosurgery, Cairo University Hospital, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Foix-Alajouanine syndrome (FAS) is an uncommon neurological disorder marked by the gradual development of spinal cord congestion. First documented by Foix and Alajouanine in 1926. Although it is infrequent, delayed or misdiagnosis is nonetheless prevalent, resulting in inadequate therapy and unfavorable results. Methods: Using the PubMed database, MEDLINE, and EMBASE, we collected data on FAS patients and conducted a pooled analysis. The term 'FAS' was used to search for related articles. Our search was restricted to previous clinical case reports or series that were published in English. Non-English articles were excluded. We included the articles in the period from 1974 to 2024. Articles were eligible if the radiographic and clinical findings were indicative of FAS. A thorough research analysis was performed, examining case reports that specifically addressed this issue. This study examines the clinical symptoms, difficulties in diagnosis, methods of treatment, and outcomes related to FAS. Results: FAS predominantly impacts the elderly population. A total of 26 patients were diagnosed with FAS. The median age of affected individuals was 53 (SD ±15.96). The ratio of males to females is roughly 5:1. The clinical manifestations encompass gradual muscle weakness and sensory impairments. The diagnosis is dependent on radiological evaluations, specifically MRI and digital subtraction angiography. Possible treatments include endovascular therapy, surgical closure of arteriovenous fistula, or a combination of the two. Significant improvements in neurological impairments can be achieved by early intervention. Conclusion: The diagnosis of FAS continues to be difficult due to its infrequency and varied clinical manifestations. Prompt and precise diagnosis is essential for proper intervention, typically utilizing endovascular or surgical methods. Additional research is required to determine prognostic markers and enhance long-term care techniques for this rare neurological condition.

Indexed as

arteriovenous fistulasFoix–Alajouanine syndromespinal cord ischemia

Identifiers

PMID39525713
PMCPMC11543206

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.