ArticleClinical kidney journal2024
Bidirectional association of sleep disorders with chronic kidney disease: a systematic review and meta-analysis.
Article in Clinical kidney journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Artificial Intelligence Diagnosis of Obstructive Sleep Apnea Using Overnight Pulse Oximetry: A Systematic Review and Bayesian Meta-Analysis.Journal of medical Internet research · 2026Pooled it
- The risk of chronic kidney disease or proteinuria with long or short sleep duration: a systematic review and meta-analysis of cohort studies.Clinical and experimental nephrology · 2025Pooled it
- Plasma proteomics of sleep traits reveals systemic immune-metabolic pathways and genetically prioritized proteins.Molecular psychiatry · 2026Article
- Sleep Disturbances in Chronic Kidney Disease - The CKD-REIN Cohort Study.Kidney medicine · 2026Article
- Over-hydration as a key modifiable predictor of obstructive sleep apnea severity in dialysis patients with daytime sleepiness.Medicine · 2026Article
- Exploratory Analysis of Pruritus and Sleep Outcomes After LCR35 Supplementation in Maintenance Hemodialysis: A Randomized, Open-Label Controlled Study.Life (Basel, Switzerland) · 2026Article
- Comparative analysis of excessive daytime sleepiness and sleep apnea symptoms in renal transplant recipients and a historical dialysis cohort.Journal of Taibah University Medical Sciences · 2026Article
- Latent profile analysis identifying symptom clusters of fatigue, sleep disturbance, pain, and anxiety and their associations with health-related quality of life and self-efficacy in patients undergoing peritoneal dialysis: a cross-sectional study.Health and quality of life outcomes · 2026Article
- Factors associated with insomnia in hemodialysis patients: A protocol for systematic review and meta-analysis.PloS one · 2026Article
- Analysis of potential categories of sleep problems in non-dialysis patients with chronic kidney disease.Frontiers in physiology · 2026Article
- Sleep disorders in renal patients: a comparative analysis of dialysis and post-renal transplant outcomes.Scientific reports · 2025Article
- Psychosocial pathways linking family support to sleep disorders in maintenance hemodialysis: the chain mediating role of depression and fatigue.Renal failure · 2025Article
- From Normal Variation in Sleep to Clinical Sleep Disorders: Genetic Insights from Over One Million Individuals.medRxiv : the preprint server for health sciences · 2025Article
- Sleep-Related Disorders in Patients with CKD and Kidney Transplant Recipients.Clinical journal of the American Society of Nephrology : CJASN · 2025Review
- The Important Role of Sleep in CKD Prevention and Progression.Kidney international reports · 2025Article
- Association between self-reported sleep disorders and prevalence of chronic kidney disease in a nationally representative sample of U.S. adults.Frontiers in psychiatry · 2025Article
- Prevalence and Factors Associated with Insomnia Among Chronic Disease Patients in Bangladesh: A Machine Learning Study.Nature and science of sleep · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Published studies have suggested a link between chronic kidney disease (CKD) and sleep disorders, although the exact nature of this association has not been uniformly described. Clarifying this relationship may facilitate evidence-based interventions that address the interplay between these disease entities. Such interventions could prevent obstructive sleep apnea (OSA) from worsening CKD and improve the quality of life for CKD patients by reducing the risk of developing OSA. Therefore, the objective of this meta-analysis is to assess the bidirectional association between sleep disorders and CKD. Methods: Following a PROSPERO-registered protocol, three blinded reviewers conducted a systematic review of the Medline/PubMed, Embase, Cochrane Library and Cumulative Index of Nursing and Allied Health (CINAHL) databases for observational studies pertaining to the relationship between sleep disorders and CKD. A meta-analysis was conducted in risk ratios (RRs). Results: From 63 studies (26 777 524 patients), OSA [RR 1.68; 95% confidence interval (CI) 1.45 to 1.93], albuminuria (RR 1.54; 95% CI 1.18 to 1.99), restless leg syndrome (RLS) (RR 1.88; 95% CI 1.48 to 2.38) and insomnia (RR 1.24; 95% CI 1.01 to 1.54) were significantly associated with CKD. There was a significant association between OSA (RR 1.77; 95% CI 1.56 to 2.01) with incident CKD. There was a significant association of OSA (RR 1.74; 95% CI 1.55 to 1.96), RLS (RR 1.73; 95% CI 1.32 to 2.25) and insomnia (RR 1.14; 95% CI 1.03 to 1.27) in patients with CKD compared with healthy controls. CKD was also significantly associated with incident OSA (RR 1.60; 95% CI 1.35 to 1.89). Conclusion: The bidirectional associations of obstructive sleep apnea with CKD remained consistent across different stages of CKD, modes of diagnosis of sleep disorder and geographical region. A bidirectional association was observed between CKD and obstructive sleep apnea, RLS and insomnia. The treatment of sleep disorders may reduce the risk of CKD, and vice versa.
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