Evidence map›Paper›PMID 39525523›Full record

ArticleLaryngoscope investigative otolaryngology2024

Prognosis of asymptomatic endolymphatic hydrops in healthy volunteers: A five-year cohort study.

Takahiro Kimura, Tadashi Kitahara, Tadao Okayasu, Masaharu Sakagami, Tomoyuki Shiozaki, Hiroshi Inui, Toshizo Koizumi, Mariko Kakudo

Abstract read
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Global research trends in magnetic resonance imaging and Meniere's disease: A bibliometric and visualized study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Takahiro KimuraDepartment of Otolaryngology-Head and Neck Surgery Nara Medical University Nara Japan.
Tadashi KitaharaDepartment of Otolaryngology-Head and Neck Surgery Nara Medical University Nara Japan.ORCID https://orcid.org/0000-0002-5260-6202
Tadao OkayasuDepartment of Otolaryngology-Head and Neck Surgery Nara Medical University Nara Japan.ORCID https://orcid.org/0000-0002-0811-1405
Masaharu SakagamiDepartment of Otolaryngology-Head and Neck Surgery Nara Medical University Nara Japan.
Tomoyuki ShiozakiDepartment of Otolaryngology-Head and Neck Surgery Nara Medical University Nara Japan.
Hiroshi InuiDepartment of Otolaryngology-Head and Neck Surgery Nara Medical University Nara Japan.ORCID https://orcid.org/0000-0002-3703-5288
Toshizo KoizumiDepartment of Otolaryngology-Head and Neck Surgery Nippon Life Hospital Osaka Japan.ORCID https://orcid.org/0000-0002-2682-4329
Mariko KakudoDepartment of Otolaryngology Takai Hospital Nara Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study aimed to clarify the prognosis of asymptomatic endolymphatic hydrops (EH) in healthy volunteers via five-year follow-ups with inner ear magnetic resonance imaging (MRI). Methods: Inner ear MRI was performed on 115 participants recruited as controls in a previous study on Meniere's disease. The endolymphatic space was visualized using Naganawa's method of contrast-enhanced MRI with intravenous gadolinium injection and evaluated using Nakashima's method of 2D imaging analysis. Results: Cochlear or vestibular EH was present in 7.0% of participants ( Conclusions: Approximately 7% of healthy participants showed asymptomatic EH. Therefore, EH is not the definitive marker for making a diagnosis of Meniere's disease or the suitable predictor for the development of Meniere's disease. Among these participants, 25% maintained EH and subsequently developed typical Meniere's disease within the next 5 years. Schellong-positive participants maintained persistent EH in the inner ear, and participants with higher scores on the self-rating depression scale developed Meniere's symptoms after 5 years. Level of evidence: 2a.

Indexed as

asymptomatic endolymphatic hydropsautonomic nervous dysregulationdepressionhealthy controlsinner ear gadolinium‐enhanced MRIMeniere's disease

Identifiers

PMID39525523
PMCPMC11541604

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.