Evidence map›Paper›PMID 39525177›Full record

ArticleCureus2024

Bupropion Toxicity Causing Refractory Cardiogenic Shock Successfully Treated With Mechanical Circulatory Support: A Case Report.

Salem Vilayet, Abubakr Adala, Munsef Barakat, Chakradhari Inampudi, George Carter, Aravind Menon

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Salem VilayetNephrology, Medical University of South Carolina, Charleston, USA.
Abubakr AdalaMedicine, Leicester Royal Infirmary, Leicester, GBR.
Munsef BarakatNephrology, Medical University of South Carolina, Charleston, USA.
Chakradhari InampudiCardiology, Medical University of South Carolina, Charleston, USA.
George CarterPulmonary and Critical Care Medicine, Medical University of South Carolina, Charleston, USA.
Aravind MenonPulmonary and Critical Care Medicine, Medical University of South Carolina, Charleston, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bupropion is a norepinephrine-dopamine reuptake inhibitor that is commonly used as an antidepressant and for smoking cessation. Bupropion overdose can lead to serious side effects which include seizures, status epilepticus, and fatal arrhythmias. Managing bupropion toxicity is challenging as there is no effective antidote and treatment is largely supportive. In this article, we present a case of bupropion toxicity causing profound cardiogenic shock which was treated successfully with mechanical circulatory support.

Indexed as

bupropion toxicitycardiogenic shockmechanical circulatory supportpolymorphic ventricular tachycrdiaprolonged qtc interval

Identifiers

PMID39525177
PMCPMC11545766

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.