ArticleCureus2024
Granulomatous Reaction to Lip Filler in a Patient with Ankylosing Spondylitis: A Case Report.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Hypersensitivity Reactions to Injectable Fillers and Their Impact on Cosmetic Procedure Results.Aesthetic plastic surgery · 2026Observational
- Hyaluronidase Use in Aesthetic Medicine: Formulations, Safety, and Clinical Practice.Journal of clinical medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The popularity of nonsurgical, minimally invasive cosmetic treatments has increased drastically in recent years, with lip augmentation being one of the most common. Dermatologists play an important role in the delivery of safe, evidence-based options for lip augmentation, including lip filler. Many types of filler are available to patients, and their safety profiles have been studied extensively. Adverse effects, if they do occur, are generally mild and self-limited; however, fewer data exist describing the adverse effects of fillers, particularly hyaluronic acid (HA) dermal fillers, in patients with a history of autoimmune disease. This report presents a case of a granulomatous delayed hypersensitivity reaction to HA filler in a patient with ankylosing spondylitis, which was subsequently successfully treated with hyaluronidase. As complications of cosmetic procedures affect patients' quality of life, this case highlights the importance of recognizing similar reactions to HA filler and the efficacy of hyaluronidase as a treatment option when they occur.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.