Evidence map›Paper›PMID 39525080›Full record

ArticleComputational and structural biotechnology journal2024

PIMMS-Dash: Accessible analysis, interrogation, and visualisation of high-throughput transposon insertion sequencing (TIS) data.

Adam M Blanchard, Adam Taylor, Andrew Warry, Freya Shephard, Alice Curwen, James A Leigh, Richard D Emes, Sharon A Egan

Abstract read
In one paragraph

Article in Computational and structural biotechnology journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Microbial genomics · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Adam M BlanchardUniversity of Nottingham, School of Veterinary Medicine and Science, Leicestershire LE12 5RD, United Kingdom.
Adam TaylorUniversity of Nottingham, Digital Research Services, Nottingham NG7 2RD, United Kingdom.
Andrew WarryUniversity of Nottingham, Digital Research Services, Nottingham NG7 2RD, United Kingdom.
Freya ShephardUniversity of Nottingham, School of Veterinary Medicine and Science, Leicestershire LE12 5RD, United Kingdom.
Alice CurwenUniversity of Nottingham, School of Veterinary Medicine and Science, Leicestershire LE12 5RD, United Kingdom.
James A LeighUniversity of Nottingham, School of Veterinary Medicine and Science, Leicestershire LE12 5RD, United Kingdom.
Richard D EmesNottingham Trent University, Nottingham NG1 4FQ, United Kingdom.
Sharon A EganUniversity of Nottingham, School of Veterinary Medicine and Science, Leicestershire LE12 5RD, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Motivation: Current methods for visualising and interrogating high-throughput transposon insertion mutagenesis sequencing (TIS) data requires a significant time investment in learning bioinformatics, often producing static figures that do not facilitate real time analysis. Summary: We have created an accessible web-based browser tool for visualisation and downstream analysis of high-throughput TIS data results generated by the PIMMS analysis pipeline. This includes multiple interactive and sortable tables to aid the user to identify genes of interest, enabling the user to gain a greater understanding of the genes contributing to fitness in their experimental work. PIMMS-Dash permits researchers, with any level of bioinformatics knowledge, to interrogate data sets and generate publication quality figures. Availability: PIMMS-Dash is freely available and is accessible online at https://pimms-dashboard-uon.azurewebsites.net and a Docker containerised version is available at https://github.com/Streptococcal-Research-Group/PIMMS-Dash to run locally.

Indexed as

TISTransposon Mutagenesis

Identifiers

PMID39525080
PMCPMC11550763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.