Evidence map›Paper›PMID 39525006›Full record

ArticleTranslational cancer research2024

Bioinformatics analysis reveals

Ling Gao, Wei Wang, Haishan Ma, Minghui Yin, Xuejiao Yang, Ruihui Han, Shuta Ohara, Dohun Kim, Guangyan Wang

Abstract read
In one paragraph

Article in Translational cancer research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ling Gao *Clinical Laboratory, Chuxiong Yi Autonomous Prefecture People's Hospital, Chuxiong, China.ORCID https://orcid.org/0009-0008-2686-249X
Wei Wang *Department of Neurosurgery, Chuxiong Yi Autonomous Prefecture People's Hospital, Chuxiong, China.ORCID https://orcid.org/0000-0001-6665-8612
Haishan MaClinical Laboratory, Chuxiong Yi Autonomous Prefecture People's Hospital, Chuxiong, China.
Minghui YinClinical Laboratory, Chuxiong Yi Autonomous Prefecture People's Hospital, Chuxiong, China.
Xuejiao YangClinical Laboratory, Chuxiong Yi Autonomous Prefecture People's Hospital, Chuxiong, China.
Ruihui HanClinical Laboratory, Chuxiong Yi Autonomous Prefecture People's Hospital, Chuxiong, China.
Shuta OharaDivision of Thoracic Surgery, Department of Surgery, Kindai University Faculty of Medicine, Osaka-Sayama, Japan.
Dohun KimDepartment of Thoracic and Cardiovascular Surgery, College of Medicine, Chungbuk National University and Chungbuk National University Hospital, Cheongju, Korea.
Guangyan WangClinical Laboratory, Chuxiong Yi Autonomous Prefecture People's Hospital, Chuxiong, China.ORCID https://orcid.org/0009-0000-3247-003X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Lung cancer is a major cause of cancer-related deaths worldwide. Unfortunately, non-small cell lung cancer (NSCLC) often lacks clear clinical symptoms and molecular markers for early diagnosis, which can hinder the initiation of timely treatments. In this study, we conducted an extensive bioinformatics analysis of copper-zinc superoxide dismutase (SOD1), a molecule linked to lung adenocarcinoma (LUAD) to enhance early detection and treatment approaches for this condition. Methods: A bioinformatics analysis was conducted using a dataset from The Cancer Genome Atlas (TCGA) database. Several analytical methods, such as a differential expression analysis, a Kaplan-Meier survival analysis, a clinicopathological analysis, an enrichment analysis, protein-protein interaction (PPI) network construction using the Search Tool for the Retrieval of Interacting Genes/Proteins (STRING) database, and an immunoreactivity analysis of Results: Our findings indicate that LUAD tissues exhibited significantly higher expression levels of Conclusions:

Indexed as

bioinformaticsCopper-zinc superoxide dismutase (SOD1)lung adenocarcinoma (LUAD)

Identifiers

PMID39525006
PMCPMC11543046

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.